GI hormones: Hamra 2011. GI Physiologiy
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| show | gastrin is secreted by the G cells
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| show | antrum of the stomach, duodenum and jejunum
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| what stimulates the release of gastrin? | show 🗑
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| show | it causes and increase in H+ secretion in the stomach by directly activating the pareital cells as well as indirectly activating the via eliciting histamine release from ECL cells
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| what receptor does gastrin bind to on ECL cells? what effect does this have? | show 🗑
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| besides gastrin, what else stimulates ECL and Parietal cells? | show 🗑
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| explain the problem persons with ZE face... | show 🗑
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| does gastrin have a trophic effec on parietal and ECL cells? | show 🗑
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| show | it comes form the duodenum, jejunum and ileum
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| show | H+
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| show | it will cause the release of Bicarb to neutralize the increased acidity of the GI as well as inhibiting the parietal and G-cells
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| what is secretin's nickname? | show 🗑
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| where does CCK come from? | show 🗑
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| show | the I-cells that secrete CCK are located in the duodenum
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| show | mostly FATS and also proteins.
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| show | enzymes from pancreas, bile from GB, inhibits parietal cells and inhibits gastric emptying
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| show | yup
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| CCK and secretin potentiate each other to release? | show 🗑
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| show | yes
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| what stimulates the secretion of somatostatin? | show 🗑
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| from which cells in somatostating secreted? where are these cells located? | show 🗑
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| what effect does somatostatin have? | show 🗑
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| where does IF come from? | show 🗑
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| show | it comes from K-cells in the jejunum
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| show | carbs/ fats/ proteins..... GIP = gluton
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| define an enterogastone | show 🗑
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| what is its primary function? | show 🗑
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| what did GIP stand for? what does it stand for now? | show 🗑
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| show | duodenum and jejunum
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| show | it stimulates gastric and intestinal motility
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| show | fasting... it is released everu 90 mins
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| what stimulatory effects does VIP have? | show 🗑
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| show | it inhibits gastric secretion and causes relaxation of GI smooth muscle
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| what nerve releases GRP? what effect does it have? | show 🗑
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| these two neurocrines decrease motility and and intestinal secretion... | show 🗑
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| show | neurotensin
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| show | somatostatin from pancreatic D-cells (inhibits everything!) and histamine from ECL cells (stimulates release of H+ from parietal cell
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| which candidate hormone causes a decrease in bicard and enzyme secretion from the pancreas? what releases it? | show 🗑
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| show | peptide YY.... it is released by fats
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| which candidate hormone causes increased insulin release? what releases it? | show 🗑
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| show | GLP-1... it stimulates the release of insulin and functions in ileal break
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