Antacid Therapy
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| show | Sodium Bicarb: systemically absorbed, and excessive amounts can cause metabolic alkalosis. Because of the systemic absorption, sodium bicarbonate is rarely used for the treatment of peptic ulcers.
Calcium Carbonate: can lead to hypercalcemia.
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| Non-Systemic Antacids | show 🗑
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| show | agents that neutralize stomach acidity (hydrochloric acid), lower pepsin activity, and raise the gastric pH
(do not protective barrier or coating over the ulcer)
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| show | aluminum compounds, magnesium compounds, calcium compounds, and sodium compounds
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| show | can cause constipation,
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| show | can cause diarrhea
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| Sodium Bicarb | show 🗑
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| Calcium Carbonate | show 🗑
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| show | Minimal absorption through intestine
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| show | Evaluate the patient’s pain, including type, duration, severity, and frequency.
Assess for fluid and electrolyte imbalances, especially serum phosphate and calcium levels.
Evaluate the patient’s renal and hepatic function.
Obtain drug history; notify t
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| show | Contraindications: Hypersensitivity to aluminum products and hypophosphatemia
Precautions: Hepatic and renal disease, older adults, children, and pregnancy
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| Aluminum Hydroxide Excretion | show 🗑
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| Magnesium Hydroxide Absorption | show 🗑
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| show | distribution and metabolism of these antacids are Unknown
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| show | Contraindications: GI obstruction
Precautions: Myasthenia gravis, renal impairment, diarrhea, and older adults
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| Magnesium Hydroxide Excretion | show 🗑
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| show | Absorption mostly occurs in the duodenum and depends on calcitriol and vitamin D. Food increases absorption by 10%-30%. Mean absorption varies with age. Absorption doubles during pregnancy. Solubility increases in acidic environments. Reduced absorption o
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| Calcium Carbonate Distribution | show 🗑
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| Calcium Carbonate Metabolism | show 🗑
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| Calcium Carbonate Excretion | show 🗑
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| show | Fairly rapid; within 15-30 minutes. However, this can vary if taken with food.
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| show | 0.5 hr
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| show | 1-3 hr, unavail half life
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| Magnesium Hydroxide onset | show 🗑
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| show | peak and duration of these antacids are unknown
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| show | Absorption of calcium varies with age.
During pregnancy, calcium absorption doubles.
Calcium absorption is reduced in achlorhydria and uremia.
The absorption of calcium depends on calcitriol and vitamin D.
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| Which time frame describes when a patient will begin to experience relief from treatment with magnesium hydroxide? 0.5 to 6 hours 8 to 12 hours 20 to 24 hours 36 to 72 hours | show 🗑
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| Contraindications and Precautions for Calcium Carbonate | show 🗑
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| show | Assess the patient’s GI status.
Monitor the patient’s laboratory values, especially electrolytes like calcium and phosphate.
Monitor lung sounds, especially in patients with heart failure, because some antacids are high in sodium, which can potentiate h
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| Which patient parameters would a nurse ensure are assessed before a patient receives calcium carbonate? Weight Calcium levels Renal function Blood pressure (BP) Phosphate levels | show 🗑
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| Which patients would a nurse determine require cautious use or avoidance of aluminum hydroxide? A 51-year-old patient with gout A 29-year-old patient who is pregnant A 71-year-old patient with dyslipidemia A 55-year-old patient with chronic kidn | show 🗑
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| Which statement by the nursing student in regard to the pharmacokinetic parameters of calcium carbonate requires further intervention? “The solubility of calcium is decreased in an acidic environment.” “Calcium carbonate distributes primarily into b | show 🗑
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| show | Aluminum hydroxide is a non-systemic antacid that can cause constipation.
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| show | 30 minutes
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| show | Raise gastric pH
Lower pepsin activity
Neutralize stomach acidity
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| show | Decreased absorption and efficacy of phenytoin
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| Which effect would a nurse monitor for in a patient who is receiving glipizide, a sulfonylurea, and aluminum hydroxide? Diarrhea Hypoglycemia Hyperglycemia Aluminum toxicity | show 🗑
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| Which patients would a nurse determine have precautions to treatment with calcium carbonate? Select all that apply. A patient with osteoporosis A patient with prostate cancer A patient with type 2 diabetes mellitus A patient with hypoparathyr | show 🗑
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| show | Take calcium carbonate 1 to 2 hours after ciprofloxacin.
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| show | Aluminum hydroxide
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Created by:
adricela55