common cardiovasclar and related drugs
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| Norepinephrine | show | Intense vasoconstriction causes reflex bradycardia which overwhelms weak B1 cardiostimulatory effects.
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| show | Isuprel | Stimulates heart more than epinephrine due to direct effects and response to decreased mean arterial pressure.
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| show | Intropin | B1 effects: increased contractility & systolic pressure, less effect on rate than isoproterenol. Causes indirect release of norepinephrine which is offset by inhibition of norepinephrine release via presynaptic dopamine receptors.
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| Phenylephrine | Neo-Synephrine | show 🗑
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| Metaproternol | show | Few cardiac effects due to lack of affinity for B1 receptors.
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| Albuterol | Ventolin, Proventil | show 🗑
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| Salmeterol | show | Few cardiac effects due to lack of affinity for B1 receptors.
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| show | Maxair | Few cardiac effects due to lack of affinity for B1 receptors.
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| show | Xopenex | Few cardiac effects due to lack of affinity for B1 receptors.
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| Amphetamine | show 🗑
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| Methamphetamine | show | Increased contraction decrease HR (reflex increase mean arterial pressure)
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| Ephedrine | show 🗑
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| show | Miochol-E | None
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| Carbachol | Carbastat, Miostat | show 🗑
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| Methacholine | Provocholine | show 🗑
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| Nicotine | show 🗑
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| Neostigmine | Prostigmine | show 🗑
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| show | Tensilon, Reversol | Used in diagnosis of Myasthenia gravis.
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| Atropine | show 🗑
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| Vecuronium | Norcuron | show 🗑
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| Pancuronium | Pavulon | show 🗑
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| Succinylcholine | Anectine | show 🗑
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| show | Novocain | Local Anesthesia
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| show | Elavil | Major depression
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| show | Prozac | Depression, OCD, Bulimia nervosa
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| show | Zoloft | Depression, OCD, Bulimia nervosa, Panic disorder.
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| Paroxetine | show | Depression, OCD, Panic disorder
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| Citalopram | Celexa | show 🗑
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| Escitalopram | Lexapro | show 🗑
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| show | Effexor | Depression, Anxiety, may worsen hypertension
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| Alprazolam | Xanax | show 🗑
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| Bupropion | Wellbutrin | show 🗑
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| show | Cymbalta | Depression, Diabetic neuropathic pain
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| show | Adderall | ADD, ADHD, Narcolepsy
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| Methylphenidate | Ritalin | show 🗑
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| Caffeine | show | Prolonged apnea in preterm infants
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| Theophylline | show 🗑
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| Chlorpromazine | show | Psychoses
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| Haloperidol | show | Psychoses, Tourettes syndrome, severe behavioral problems in children, hyperactive children, Hunington's disease & Alcohol withdrawl
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| Promethazine | Phenergan | show 🗑
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| Scopolamine | show | Motion sickness, nausea
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| Metoclopramide | show | Nausea in chemotherpy patients, GI stimulant to improve gastric emptying
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| Levodopa | L-dopa | show 🗑
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| Morphine | show 🗑
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| Oxycodone | show | Moderate to severe pain
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| Hydrocodone | show 🗑
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| show | Dilaudid | Moderate to severe pain
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| Meperidine | show | Severe pain
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| show | Sublimaze | Pain management pediatrics
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| Codeine | show 🗑
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| Nalbuphine | Nubain | show 🗑
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| Naloxone | Narcan | show 🗑
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| show | ReVia | Treatment of alcoholism
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| Clonazepam | Klonopin | show 🗑
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| Midazolam | show | Moderate sedation
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| Temazepam | show | Anxiety disorder
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| Triazolam | Halcion | show 🗑
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| show | Generalized seizures in pediatric patients
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| Diazepam | Valium | show 🗑
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| Lorazepam | show | Rapid sedation of agitated patients, status epilepticus
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| show | Tegretol | All seizure types but absence
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| Valproic Acid | show | All seizure types
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| Gabapentin | show | Partial seizures
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| Nitrous Oxide | show | Most commonly used in pediatrics & dental procedures
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| show | Diuril | Good starting agent for treating hypertension, chronic edema, Idiopathic hypercalcuria. May cause electrolyte imbalance
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| Furosemide | show | Quick acting, only given every 6 hrs. May cause electrolyte imbalance. PO, IV
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| Torsemide | Demadex | show 🗑
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| show | Bumex | Most potent, edema, pulmonary edema. May cause electrolyte imbalance, PO, IV not given at home.
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| show | Aldactone | Edema, hypertension. Causes endocrine imbalance. PO
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| Mannitol | show | Acute renal failure, acute closed angle glaucoma, brain edema, & some drug overdoses. Causes headache, nausea, vomiting, chills, dizziness, polydipsia, lathargy, confusion & chest pain. Most common used for cerebral edema
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| Clonidine | show | Mild to moderate hypertension. Causes rash drowsiness, dry mouth, constipation, headache, impaired ejaculation, rebound hypertension if stopped abruptly. Starting dose low to limit toxicity.
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| show | Aldomet | Hypertension in pregnant women. Causes dry mouth, slight orthostatic hypotension. Some patients experience impotence, psychic disturbances, nightmares, involuntary movements or hepatotoxicity.
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| show | Cardura | Hypertension with congestive heart failure. Can cause hypotension, sodium depletion, edema, dry mouth, congestion, headache, nightmares, sexual dysfunction & lethargy. PO
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| Labetalol | Trandate, Normaodyne | show 🗑
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| show | Coreg | Hypertension, Tachycardia. Can cause further suppression of failing heart, fatigue, impotence, diarrhea, numbness, orthostatic hypotension. PO, IM, IV
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| Atenolol | Tenormin | show 🗑
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| Carteolol | Cartrol | show 🗑
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| show | Levatol | Hypertension. Further supresses failing heart. PO
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| show | Zebata | Hypertension. Further supresses failing heart. PO
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| show | Lopressor | Hypertension. Further supresses failing heart. PO
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| show | Brevibloc | Cardiosuppression in acute MI & unstable angina. Decreases HR & BP. IV
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| show | Inderal | Cardiosuppression in acute MI & unstable angina. Produces transient hypertension & bronchospasm. PO
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| Nadolol | Corgard | show 🗑
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| show | Capoten | Hypertension. Enhances heart reperfusion in MI patients. First dose can cause hypotension, dizziness, proteinuria, rash, tachycardia & headache. PO
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| Lisinopril | Prinivil | show 🗑
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| Enalapril | Vasotec | show 🗑
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| show | Lotensin | Hypertension. Enhances heart reperfusion in MI patients. First dose can cause hypotension, dizziness, proteinuria, rash, tachycardia & headache. PO
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| Losartan | show | Hypertension. Can cause hypotension & dizziness. PO
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| Valsartan | Diavan | show 🗑
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| show | Avapro | Hypertension. Can cause hypotension & dizziness. PO
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| Candesartan | show | Hypertension. Can cause hypotension & dizziness. PO
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| Telmiscartan | show | Hypertension. Can cause hypotension & dizziness. PO
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| show | Apresoline | Moderate hypertension. Used with caution in pregnant women.Can cause reflex tachycardia, palpitationa, fluid retension systemic lupus erthematosis-like syndrome
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| Nifedipine | Procardia | show 🗑
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| show | Cardene | n/a
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| Amiodipine | show | n/a
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| Nitroglycerin | show 🗑
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| Digoxin | Lanoxin | show 🗑
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| Dobutamine | Dobutrex | show 🗑
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| show | Natrecor | n/a
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| show | n/a
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| show | Pronestyl | n/a
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| Disopyramide | Norpace | show 🗑
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| Lidocaine | Xylocaine | show 🗑
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| Flecainide | show | n/a
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| show | Rhythmol | n/a
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| show | Inderal | n/a
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| show | Kerlone | n/a
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| Amiodarone | show | n/a
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| Dofetilide | show | n/a
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| Sotalol | Betapace | show 🗑
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| show | n/a
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| Adenosine | Adenocard | show 🗑
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| show | Mevacor | n/a
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| Simvastatin | Zocor | show 🗑
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| Pravastatin | show | n/a
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| Atorvastatin | Lipitor | show 🗑
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| show | Crestor | n/a
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| Ezetimibe | Zetia | show 🗑
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| show | n/a
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| show | n/a
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| Clopidogrel | show | n/a
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| Cilostazol | show | n/a
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| Dipyridamole | show | n/a
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| show | ReoPro | n/a
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| Eptifibatide | Intergrilin | show 🗑
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| show | Aggrastat | n/a
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| Streptokinase | show 🗑
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| Urokinase | show | n/a
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| Tissue Plasmiogen Activator | show | n/a
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| show | Activase | n/a
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| Reteplase | Retavase | show 🗑
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| show | Angiomax | n/a
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| Hydrochlorothiazide | show | Most common Thiazide
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| Epinephrine | show | All cardiac effects mediated by B1; increased HR, contractility, conduction velocity & automaticity of AV-node, HIS, purkinje fibers & ventricles
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