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Inflammation & Repair

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Question
Answer
Inflammation resulting in a coagulating exudate rich in protein is known as   fibrinous  
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interaction between antigens and antibodies activates complement mediators that attract   leukocytes  
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class of drugs that can be used to treat persistent inflammation   corticosteroids  
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acute spreading infection of the skin and deeper tissues is known as   cellulitis  
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results from an area of tissue breakdown with accumulation of pus   abscess  
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Septicemia is an infection of   the blood  
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factors that influence the outcome of an infection include   virulence, dosage, & resistance of the host's body  
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inflammatory reaction   nonspecific reaction to any agent that causes cell injury  
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agent's that can induce an inflammatory reaction include   physical, chemical, or microbiologic  
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inflammatory reaction is characterized by   local & systemic effects  
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local effects of inflammatory response consists of   dilation blood vessels & increased vascular permeability  
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adhere to endothelium of small blood vessels, force their way through walls & migrate to area of tissue damage   leukocytes during an inflammatory response  
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heat, redness, tenderness, swelling & pain are   characteristics of inflammation  
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leakage of plasma from dilated more permeable vessels causes volume of fluid in inflamed tissue   to increase, thus swelling  
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dilatation of capillaries & slowing of blood through vessels causes   increased warmth & redness to inflamed tissues  
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the secondary tenderness & pain at site of inflammatory process is   the associated irritation of sensory nerve endings  
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the most important cell in acute inflammatory response is   the polymorphonuclear leukocyte  
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polymorphonuclear leukocyte, attracted to the area by cell injury, is   a phagocytic cell  
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cells that appear later in process, clean up debris produced by inflammatory reactions   mononuclear cells  
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mononuclear cells are   monocytes & macrophages  
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exudate   fluid mixture of protein, leukocytes, & debris that forms during inflammatory process  
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serous exudate   fluid consisting of very little protein  
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if a large amount of serous exudate accumulates in injured tissue it may form   blisters  
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purulent exudate   creamy, yellow fluid consisting largely of inflammatory cells  
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pus is   purulent exudate  
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fibrinous exudate   fluid rich in blood protein fibrinogen  
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fibrinogen coagulates and forms   fibrin, producing sticky film on surface of inflamed tissue  
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hemorrhagic exudate   occurs when inflammatory process rupture many small capillaries, allowing RBCs escape into tissues; exudate appears bloody  
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if fibrinous exudate involves 2 surfaces in close proximity, they may   stick together  
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adhesions   bands fibrous tissue form subsequent to inflammation & bind adjacent tissues together  
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systemic effects become evident when   inflammatory process is severe  
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bone marrow accelerates production of leukocytes circulating in blood stream increases & person feels ill w/fever are   systemic effects of inflammatory response  
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systemic effects of inflammation also cause liver to produce   acute phase proteins, released into bloodstream in response to tissue injury/inflammation  
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acute phase proteins   help protect body from injury of tissue due to the inflammation  
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often measured to monitor activity of diseases characterized by inflammation   C reactive protein  
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resolution   regression of inflammatory process with significant tissue destruction & tissues returns to normal  
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mediators   formed & released when tissue is damaged  
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some mediators are derived from cells & other from   proteins in plasma accumulation at injury site  
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mast cells   specialized connective-tissue cell containing granules filled w/histamine & other chemical mediators  
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initiate the inflammatory process   mast cells  
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vasodilator   substance that dilates blood vessels  
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potent vasodilator of inflammatory response is   histamine  
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in regards to inflammatory response, blood platelets contain   histamine & serotonin  
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serotonin   vasoconstrictor mediator released from platelets  
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serotonin is released when   platelets adhere to collagen fragments at site of tissue injury  
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prostaglandins   compels derivative of fatty acid, prostanoic acid, having widespread physiological effects  
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major source of cell derived mediators   mast cells  
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leukotrienes   prostaglandin-like mediator of inflammation  
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function as mediators that intensify inflammatory process   leukotrienes & prostaglandins  
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leukotrienes & prostaglandins are synthesized from arachidonic acid present in   cell membranes in response to stimuli that induce inflammatory response  
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bradykinin   chemical mediator of inflammation derived from components in blood plasma  
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protein substances circulating in blood plasma as inactive compounds leak from   permeable capillaries into area of tissue damage, then activated into chemical mediators  
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series of reactions leading to formation of bradykinin is triggered by   one of proteins concerned with blood coagulation, activated by tissue injury  
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complement   several separate protein components that interact in regular sequence to yield series of by-products  
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by-products of function as mediators of inflammation   complement  
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complement are designated   C1 through C9  
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granules contained in chemical mediators which attract phagocytic neutrophils & monocytes are   lysosomes  
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lysosomes   contain potent enzymes that capable digesting material brought into cytoplasm of cells by phagocytosis  
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much of tissue injury in an area is result of   destructive effect of lysosomal enzymes released from leukocytes, most of which during phagocytosis  
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interaction of antigen & antibody activates   complement, & mediators generate induce inflammatory reaction  
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adrenal corticosteroid hormones are administered   when inflammatory process persists causing extensive, progressive tissue injury  
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inflammation caused by disease-producing organism is   an infection  
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-itis is appended to name of tissue/organ to indicate   infection or inflammatory process  
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cellulitis   scute spreading inflammation affecting skin or deeper tissues  
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abscess   localized accumulation of pus in tissues  
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lymphangitis   inflammation of lymph vessels draining a site of infection  
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septicemia   infection in which large numbers of pathogenic bacteria are present in the blood stream  
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pathogenic   capable of producing disease  
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virulence   ability of organism to cause disease  
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highly virulent organism is likely to produce disease in   majority of susceptible individuals  
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low virulent organism is likely to produce disease in   individual only under favorable circumstances  
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when organism & host are evenly matched clinically results in   chronic infection  
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different terms are used to describe infections in   different sites  
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nonspecific & characterized by both local & systemic effects   inflammation  
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inflammation of lymph nodes draining at a site of infection   lymphadenitis  
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used to refer to an overwhelming infection in which pathogenic bacteria gain access to the bloodstream   septicemia  
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extensive destruction of tissue, which is secondary to inflammation, is often followed by   scarring  
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scarring, due to a severe inflammation, can be so severe it causes   serious malfunction of tissues, or disturbed function  
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