AH Bone
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show | A connective tissue characterized by a mineralized extracellular matrix. The mineral is hydroxyapatite crystals.
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show | To support and protect our bodies, and due to its mineral content, it also is a storage site for calcium and phosphate. Both can be mobilized from the bone matrix and taken up by the blood as needed to maintain appropriate levels throughout the body.
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show | Spaces called lacunae contains a bone cell, osteocyte. The osteocyte extends processes into small tunnels called canaliculi. These connect adjacent lacunae and allowing contact between the cell processes of neighboring osteocytes.
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What other cells are present in bone? | show 🗑
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What are the two classifications of bone tissue? | show 🗑
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show | Long Bones Short Bones Flat Bones Irregular Bone
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show | Bones are covered by periosteum, a sheath of dense fibrous connective tissue containing osteoprogenitor cells.
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What is the endosteum? | show 🗑
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show | The marrow cavity and the spaces in spongy bone contain bone marrow. Red marrow has developing blood cells, yellow marrow is no longer developing and is full of fat.
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show | Structural units called osteons (Haversian systems). They consist of concentric lamellae of bone matrix, surrounding a central canal which contains the vascular and nerve supply of the osteon. Canaliculi arranged in a radial pattern.
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show | Between the osteons are remnants of previous concentric lamellae.
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show | Similar to compact bone. However, arranged as trabeculae or spicules, numerous interconnecting marrow spaces of various size are present between the bone tissue. Matrix is lamellated. If the trabeculae are sufficiently thick, they will contain osteons.
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How does immature bone differ from mature bone? | show 🗑
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show | 1. Intramembranous Ossification 2. Endochondral Ossification
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How does intramembranous ossification occur? | show 🗑
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show | Hyalin Cartilage model Cuff of bone around it Periosteal bony collar Chondrocytes in midregion of cartilage model become hypertrophic. Calcified matrix causes death of chondrocytes. Periosteal cells migrate into the cavity.
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show | resorption: Nearest the diaphysis. The calcified cartilage here is in direct contact with the connective tissue of the marrow cavity.
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mattdomin