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Veterinary Terminology Hematologic/Lymphatic and Immune Systems

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blood   supplies body tissues with oxygen, nutrients (such as vitamins, minerals, glucose, and amino acids)  
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hem/o, hemat/o   combining form for blood  
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hermatology   the study of blood  
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hematopoiesis   is the medical term for formation of blood  
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-poiesis   means formation  
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drawing blood   is a common term for collecting a blood sample  
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anticoagulant   is a substance that prevents blood from clotting  
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EDTA/heparin   are types of anticoagulants found in blood tubes and are used clinically as drugs.  
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coagulation   is the process of clotting  
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buffy coat   the layer that appears at the interface of the erythrocytes and plasma after blood has been centrifuged  
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serum   is the liquid portion of blood with clotting proteins removed  
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plasma   is the straw-colored fluid portion of blood that transports nutrients, hormones, an waste products  
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colloid   a liquid that contains suspended particles (in the case of plasma, most of the suspended particles are clotting proteins)  
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fibrinogen/prothrombin   clotting proteins found in plasma  
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fibrin/o   means fibrin or threads of a clot  
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pro-   prefix mean before  
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thromb/o   combining form means clot  
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albumin   another example of a plasma protein  
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cholesterol/triglyceride   are types of lipids that circulate in the blood  
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erythrocyte   is a mature red blood cell (oxygen- carrying cell) abbr. RBC  
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erythr/o   means red  
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-cyte   suffix means cel  
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hemoglobin   a blood protein that transports oxygen  
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heme   is the nonprotein, iron-containing portion of hemoglobin  
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central pallor   central pale area of an RBC that represents the thinnest part of the biconcave disc  
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myel/o   combining form for bone marrow/spinal cord  
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reticulocyte   is an immature, non -nucleated erythrocyte characterized by polychromasia (Wrights stain) or a mesh like pattern or threads (new methylene blue stain)  
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reticulocytosis   is seen with regenerative anemia because bone marrow is responding to blood loss  
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macrophage   is a large cell that destroys by eating (engulfing)  
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macr/o   means large  
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-phage   suffix means eating  
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phagocyte   is" a cell that eats"  
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hematology   is the study of blood  
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morphology   study of form or shape  
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leukocyte   is a white blood cell abbr WBC  
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leuk/o   means white  
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leukocytopoiesis   is the production of white blood cells  
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leucopoiesis   production of leukocytes  
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granulocyte   is a cell that contains prominent grain like structures in its cytoplasm  
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agranulocyte   is a cell that does not contain prominent grain like structures in its cytoplasm  
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basophilic   means stained readily with basic, or blue, dyes in many commonly used stains such as hematoxylin and eosin (H&E), Giemsa, and Wrights  
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eosinophilic   means stained readily with acidic, or pink, dyes in many commonly used stains as H&E, Giemsa, and Wright's  
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normocytic   normal cell size  
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macrocytic   larger-than-normal cell size  
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microcytic   smaller-than-normal cell size  
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poikilocytosis   condition of irregular cells; clinically means varied shapes or erythrocytes  
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poikilo   means irregular  
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anisocytosis   condition of unequal cell size; excessive variation in RBC size  
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normochromic   normal RBC color (has area of central pallor of normal size)  
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hypochromic   less-than-normal color (has enlarged area of central pallor)  
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hyperchromic   more-than-normal color ( term is not commonly used)  
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polychromasia   condition of many colors that appears as an overall blue tint of wright-stained RBC's due to shrinking of the cell membrane; indicates slight immaturity of the erythrocyte  
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rouleaux   RBC that are arranged like stacks of coins on the peripheral blood smear; may be artifact or may be normal in species such as cats and horses  
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agglutination   clumping of RBC's due to the presence of an antibody directed against RBC surface antigens that forms a latticework that links them together  
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lymphocyte   class of "agranulocytic"leukocyte that contains a diverse set of cells including those that can directly attack specific pathogens or produce antibodies  
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monocyte   class of "agranulocytic" leukocyte that has a phagocytic function and participates in the inflammatory response  
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neutrophil   class of granulocytic leukocyte that has phagocytic function (mainly against bacteria)  
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segmented neutrophil or polymorphonuclear leukocyte   a mature neutrophil  
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polymorphonuclear   means multi shaped nucleus  
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band cell or banded neutrophil   is a immature PMN (polymorphonuclear)  
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heterophils   which are neutrophils that found in rabbits, birds, amphibians, and reptiles and are large and stain a deep orange or red  
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eosinophil   class of granulocytic leukocyte that detoxifies allergens and controls parasitic infections by damaging parasite membranes  
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basophil   class of granulocytic leukocyte that promotes the inflammatory response and contains histamine in its cytoplasmic granules  
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thrombocyte   is a nucleated clotting cell  
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platelet   is an anucleated clotting cell  
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megakaryocyte   is a large, nucleated cell found in the bone marrow from which platelets are formed  
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blood smear   blood specimen for microscopic examination in which blood is spread thinly across a microscope slide and typically stained.  
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bone marrow biopsy   sample of bone marrow obtained by needle aspiration for examination of cells  
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ultrasound   diagnostic procedure to image the structures of blood vessels (diagnostic ultrasound) and flow of blood through these vessels  
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anemia   blood condition of less-than-normal levels of red blood cells and/or hemoglobin  
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basopenia   deficiency in the number of basophils in the blood  
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-penia   is a suffix that indicates a decrease in a particular type of cell  
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basophilia   elevation in the number of basophils in the blood  
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-philia   is the suffix that indicates an increase in a particular type of cell  
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disseminated intravascular coagulation   disorder in which the proteins that control blood clotting become abnormally active, producing clots that obstruct the blood vessels, cut off blood supply to various organs, and in time alter the functioning of these organs.  
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dyscrasia   any abnormal condition of the blood  
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edema   accumulation of fluid in the intercellular space  
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edemateous   is the adjective form of edema  
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eosinopenia   deficiency in the number of eosinophils in the blood  
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eosinophilia   elevation in the number of eosinophils in the blood  
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erythrocytosis   abnormal increase in red blood cells  
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-cytosis   means condition of cell but implies elevated cell numbers  
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exudate   material that has escaped from blood vessels and is high in protein,cells, or solid materials derived from cells  
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hemolytic   removing and destroying red blood cells  
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hemolytic anemia   is excessive RBC destruction; resulting in lower-than-normal levels of RBC  
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hemolytic serum   contains red blood cell components that are released when erythrocytes are damaged due to a variety of causes (such as improper specimen processing, collection, or transport) and appears pink or blood-tinged  
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hemolysis   is the breaking down of red blood cells  
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lysis   is the medical term for destruction or breakdown  
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lipemic   serum contains an excessive amount of fat and appears white  
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hemolytic   serum contains red blood cell components that are released when erythrocytes are damaged due to a variety of causes and appears pink or blood tinged  
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icteric   serum is yellow tinged due to increased bilirubin levels  
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normal   serum is clear  
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hemophilia   hereditary condition of deficient blood coagulation  
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hemorrhage   loss of blood (usually in short period of time)  
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hemostasis   is the act of controlling blood or bleeding  
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hemostat   is an instrument used to control bleeding  
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hyperalbuminemia   blood condition of abnormally high albumin levels  
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hyperemia   excess blood in a part; engorgement  
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hyperlipidemia   blood condition of abnormally high fat levels caused by fat metabolism  
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lip/o   combining form for fat  
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left shift   common term for an alteration in the distribution of leukocytes in which there are increases in banded neutrophils usually in response to sever bacterial infection.  
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leukemia   elevation in the number of malignant white blood cells; animals with leukemia have extremely elevated total leukocyte counts  
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leukocytosis   elevation in the number of white blood cells  
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leukopenia/leukocytopenia   deficiency of white blood cells  
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lipemia   excessive amount of fats in the blood  
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lipemia serum   fats from blood that have settled in the serum  
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lymphocytosis   elevated numbers of lymphocytes in the blood  
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lymphopenia   deficiency of lymphocytes in the blood  
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modified transudate   material that has cell numbers and distribution similar to transudates but the protein concentration is greater than 2.5 g/dL resulting from leakage of high protein; modified transudates are common in right sided heart failure  
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transudate   material that has passed through a membrane and is high in fluidity and low in protein, cells, or solid materials derived from cells; transudates are observed with sever hepatic disease, protein losing enteropathy, or protein losing nephropathy  
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thrombocytosis   elevation in number of clotting cells  
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thrombocytopenia   abnormal decrease in the number of clotting cells  
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-penia   less than normal or deficiency  
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septicemia   blood condition in which pathogenic microorganisms (bacteria) and their toxins are present  
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-emia   suffix means blood condition  
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pathogenic   means producing disease  
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bacteremia   is the blood condition in which bacteria are present  
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polycythemia   condition of many cells; clinically means excessive erythrocytes  
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phagocytosis   condition of engulfing or eating cells  
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pancytopenia   deficiency of all types of blood cells  
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neutrophilia   elevation in the number of neutrophils in the blood  
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neutropenia   deficiency in the number of neutrophils in the blood  
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myelodysplasia   hematologic disorder characterized clinically and morphologically by ineffective hematopoiesis that results in some form of cytopenia such as anemia, neutropenia, and/or thrombocytopenia  
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monocytosis   elevated numbers of monocytes in the blood  
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monocytopenia   deficiency of monocytes in the blood  
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lymph/o   means lymph fluid, lymph vessels, and lymph nodes  
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lymphoid   pertains to lymph or tissue of the lymphatic system  
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interstitial fluid   is the clear, colorless tissue fluid that leaves the capillaries and flows in the spaces between the cells of a tissue or an organ  
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lymph   is formed when interstitial fluid moves into the capillaries of the lymphatic system  
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lymph capillaries   lymph is carried from the tissue space via thin-walled tubes called  
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lymphatic vessels   are similar to veins in that they have valves to prevent the back flow of lymph  
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cisterna chyli   is the origin of the thoracic duct and saclike structure for the lymph collection  
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lacteals   locate in the small intestine, are specialized lymph vessels that transport fats and fat-soluble vitamins  
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lymph nodes   are small bean shaped structures that filter lymph and store B and T lymphocytes  
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para-   means near  
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otos   is greek for ear  
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tonsils   are masses of lymphatic tissue that protect the nose and cranial (upper) throat  
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tonsill/o   combining form for tonsil  
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spleen   is an organ located in the cranial abdomen that filters foreign material from the blood, stores erythrocytes, removes damaged or old erythrocytes, and maintains an appropriate balance of cells and plasma in the blood  
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splen/o   means spleen  
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thymus   is a gland that has an immunologic function and is found predominantly in young animals  
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thym/o   combining form for thymus  
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immunity   means exemption  
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immun/o   means protected  
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immunology   is the study of the immune system  
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lymphocyte   is a type of white blood cells that is involved in the immune response and works against specific antigens  
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antigen   is a substance that the body regards as foreign  
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antibody   is a disease-fighting protein produced by the body in response to the presence of a specific antigen.  
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B lymphocytes   are produced and mature in the bone marrow and are responsible for antibody-mediated or humoral immunity.  
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plasma cell   is an immune cell that produces and secretes a specific antibody for a specific antigen  
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plasmocytes   plasma cells are called  
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immunoglobulins   the antibodies made by plasma cells are called  
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T lymphocytes   are small, circulating lymphocytes produced in the bone marrow  
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T cells   these cells mature in the thymus  
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IgA   found in the mucous membrane lining of intestines and bronchi, and secretions such as saliva, sweat, and tears  
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IgD   found in large amounts on the surface of B cells  
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IgE   found bound to mast cells in lungs, skin, and cells of mucous membranes  
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IgG   found in blood stream, interstitial fluid (tissue) and lymph (lymph vessels)  
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IgM   found in circulating fluids (due to its size it can not leave the blood stream)  
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T cells   are responsible for cell-mediated immunity  
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helper T cells   secrete substances such as cytokines that stimulate the production of B lymphocytes and cytotoxic T cells.  
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cytotoxic T cells   destroy intracellular pathogens  
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suppressor T cells   stop B and T lymphocyte activity when this activity is no longer needed  
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memory T cells   remember a specific antigen and stimulate a faster and more intense response when the same antigen is presented to the body  
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monocytes   are another type of leukocyte formed in the bone marrow and transported to other parts of the body  
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histiocytes   are large macrophages found in loose connective tissues  
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intact   means having no cuts, scrapes, openings, or alterations  
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mut/a   means genetic change  
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complement   is a series of enzymatic proteins that are continually present in normal plasma  
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immunity   is the state of being resistant to a specific disease  
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naturally acquired passive immunity   resistance to a specific infection by the passing of protection from mother to offspring before birth or through colostrum  
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naturally acquired active immunity   resistance to a specific infection after the development of antibodies during the actual disease  
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artificially acquired passive immunity   resistance to a specific infection by receiving antiserum-containing antibodies from another host  
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artificially acquired active immunity   resistance to a specific infection through vaccination  
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allergy   overreaction by the body to a particular antigen or called hypersensitivity  
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allergen   is a substance capable of inducing an allergic reaction  
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autoimmune disease   disorder in which the body makes antibodies directed against itself  
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immunosuppression   reduction or decrease in the ability of the immune system to respond to stimulation by antigens  
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immunosuppressant   is a chemical that prevents or reduces the body's normal reaction to a disease  
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lymphadenitis   inflammation of the lymph nodes also called swollen glands  
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lymphadenopathy   disease of the lymph nodes  
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lymphangioma   abnormally collection of lymphatic vessels forming a mass (usually benign)  
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splenomegaly   enlargement of the speed  
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tonsillitis   inflammation of the tonsils  
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vaccine   preparation of pathogen(live, weakened or killed) or a portion of pathogen that is administered to stimulate a protective immune response against the pathogen  
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vaccination   administration of antigen (vaccine) to stimulate a protective immune response against a specific infectious agent  
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titer   quality of a substance required to react with a given amount of another substance  
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antibody titer   measures the concentration of antibodies circulating in the blood stream of an animal  
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resistant   not susceptible  
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opportunistic   able to cause disease (due to debilitation or alteration of the animal) when disease normally would not be produced  
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multiplication   reproduction  
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inhibit   to slow or stop  
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innate immunity   immunity determined by the genetic makeup of an individual  
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heredity   genetic transmission of characteristics from parent to offspring  
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herd immunity   resistance of a group (herd) to a microbe/infection because a large proportion of the group's member are immune  
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splenectomy   surgical removal of the spleen  
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thymectomy   surgical removal of the thymus  
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tonsillectomy   surgical removal of the tonsils  
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oncology   is the study, diagnosis, and treatment of tumors  
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tumor   does not mean cancerous  
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neoplasm   is any abnormal new growth of tissue in which the multiplication of cells is uncontrolled, more rapid than normal, and progressive.  
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apoptosis   the death of normal cells in a normal time cycle  
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pedunculated   means having a peduncle or stalk  
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anaplastic   reverting to a more immature form  
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carcinoma in situ   contained at a site (not spreading)  
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diffuse   evenly spreading  
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dysplastic   abnormal cell development  
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follicular   containing glandular sacs  
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hyperchromatic   intensely colored  
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hyperplastic   excessive cell numbers  
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hypoplastic   deficient cell numbers  
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nodular   tight cell clusters  
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pleomorphic   having many cell types  
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undifferentiated   lacking a defined cell structure  
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cystic   fluid filled  
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inflammatory   appearing red and swollen  
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medullary   large and fleshy  
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necrotic   containing dead tissue  
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ulcerating   having depressed, open areas  
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verrucous   having warlike growth  
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malignant   cancerous  
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benign   nonmalignant tumors  
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well-circumscribed   means the mass has well-defined borders  
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encapsulated   means the tumor is retained within a border of connective tissue  
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invasive   means that the mass does not have well-defined borders and is spreading  
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metastasis   is a pathogenic growth distant from the primary disease site; means beyond control  
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metastases   plural form of metastasis  
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metastasize   is used to describe invasion by the pathogenic growth to a point distant from the primary disease site.  
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carcinoma   is a malignant growth of epithelial cells  
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sarcoma   is a malignant neoplasm arising from any type of connective tissue  
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carcin/o   means cancer  
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sarc/o   means flesh  
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carcinogen   isa substance that produces cancer  
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-gen   suffix means producing  
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brush biopsies   is the passing of a catheter with bristles on it into an organ to remove cells for examination  
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needle biopsy   is any biopsy in which cells are aspirated through a needle; known as an FNA  
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exfoliative biopsy   is a biopsy in which cells are scraped off the skin for evaluation  
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histophathology   the microscopic study of the structure, composition, and function of tissues  
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chemotherapy   treatment of neoplasm through the use of chemicals  
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fulguration   destruction of tissue by high-frequency electrical current  
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lymphadenectomy   surgical removal of lymph node. The name for removal of any tissue that may have a mass or tumor can be derived by adding the combining form for there being removed  
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protocol   course of treatment  
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radiation therapy   treatment of neoplasm through the use of X-rays; abbreviated RT. Cells that are treated with high dose radiation are irradiated.  
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rads   how radiation is measured  
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radiosensitive   tumor absorbs radiation and responds by drying or shrinking  
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radioresistant   tumor is minimally affected by radiation  
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leukotrichia   whitening of the hair  
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surgical excision   removal of the entire mass in addition to some normal tissue to ensure that the entire mass is removed  
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melanoma   neoplasm composed of melanin-pigmented cells  
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myeloma   malignant neoplasm composed of muscle  
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myxoma   tumor of connective tissue  
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neubroblastoma   malignant neoplasm of nervous tissue origin  
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osteosaracoma   malignant neoplasm composed of bone  
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rhabdomyosarcoma   malignant tumor of striated muscle  
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squamous cell carcinoma   malignant tumor developed from squamous epithelial tissue  
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leiomyosarcoma   malignant tumor of smooth muscle  
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lymphoma/lymphosarcoma   general term for neoplasm composed of lymphoid tissue (usually malignant)  
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mast cell tumor   malignant growth of tissue mast cells (cells that release histamine)  
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touch preps   collections of cells on a glass slide pressed against a part of the mass  
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ultrasound   imaging of internal body structures by recording echoes of sound waves  
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adenocarcinoma   malignant growth of epithelial glandular tissue  
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blastoma   neoplasm composed of immature undifferentiated cells  
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blast/o   means immature cells  
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hemangioma   benign neoplasm composed of newly formed blood vessels  
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hemangiosarcoma   malignant tumor of vascular tissue  
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radiographs   records of ionizing radiation used to visualize internal body structures  
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