Antiepileptics, Antiparkinsons, and Psychotherapeutics
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carbamezepine | Na+ Channel blocker. Side effects are hyponatremia. Metabolized in liver. Give with meals.
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Phenytoin | Most common. Tonic-Clonic. Na+ Channel blocker. Side effects are lethargy, abnormal movements, confusion, gingival hyperplasia.
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Lamotrigine | Na+ Channel blocker. Side effects are Steven-Johnson syndrome. Metabolized in liver.
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Valporate | Na+ Channel blocker. Enhances GABA. Teratogenic. Metabolized in liver.
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Topiramate | Na+ Channel blocker. Enhances GABA. Side effects are cognitive impairment, weight loss and kidney stones. Metabolized in liver and kidney.
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Pregabalin | Side effects are ankle edema and weight gain. Metabolized in kidney.
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Levitiracetam | Side effects are depression and psychiatric issues. Metabolized in kidney.
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Epilepsy: | Neurological condition which affects the brain and nervous system by causing seizures.
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Diagnosis of Epilepsy | : EEG or MRI
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Treatment of Epilepsy | Antiepileptics, Vagus Nerve Stimulation, Surgery
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Adverse Effects of Epilepsy | N/V/D, sedation, suicidality.
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Nursing Considerations for Epilepsy | Seizure history, medications, allergies, panic attacks, autonomic nervous system responses, neurological assessment, lab results, skin assessments, oral exam, vital signs, environment assessment, vision.
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Parkinson’s Disease: | Neurodegenerative disorder that affects movement. Deficit in dopamine.
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Diagnosis for Parkinson's | Medical history, neurological examination (look for resting tremor, bradykinesia and rigidity) and DaTscan.
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Treatment for Parkinsons' | Medication, PT, OT, Speech Therapy, deep brain stimulation
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Carbidopa-levodopa | Levodopa the most effective Parkinson’s med is a natural chemical that passes into your brain and is converted to dopamine. Levodopa is combined with carbidopa which protects levodopa from premature conversion to dopamine outside your brain, which preven
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Dopamine agonists | don’t change into dopamine like levodopa
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MAO-B inhibitors | prevent the breakdown of dopamine by inhibiting the brain enzyme B
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Catechol-O-methyltransferase inhibitors | prolongs the effect of levodopa therapy by blocking an enzyme that breads down dopamine
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Anticholinergics | helps with tremors, stay away if you are older because of the kidney and liver
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Amantadine | short term relief of mild, early stage Parkinson’s disease. Symmetrel is also an antiviral.
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Anxiolytic Drugs | Alrazolam, Diazepam, Lorazepam, BuSpar
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Contraindications of Anxiolytic drugs | allergy, narrow angle glaucoma, pregnancy.
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Adverse Effects of anxiolytic drugs | Addictive, sedation
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Mood Stabilizers | Treats bipolar disorder.
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Drugs of mood stabilizers | Lithium, anti-epileptics, atypical antipsychotics.
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Antidepressants first generation Drugs | Tricyclics, Tetracyclics, MAOIs
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Antidepressants second generation drugs | SSRIs, SNRIs
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Antipsychotics | Treat serious mental illnesses such as drug-induced psychoses, mania, schizophrenia.
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Side Effects of Antipsychotics | Sedation, dry mouth, visual disturbances, flushing, constipation, weight gain, tardive dyskinesia.
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Contraindications of antipsychotics | Allergy, CNS depression, brain damage, kidney/liver disease, blood dyscrasias, uncontrolled epilepsy.
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First Generation (Typical) of psychoanalytic | Haldol
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Second Generation (Atypical) of psychoanalytic | Abilify, Clozapine, Risperdal.
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Nursing considerations of psychoanalytic | No milk with MAOIs! Black box warning for suicidal thoughts.
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