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Antiepileptics, Antiparkinsons, and Psychotherapeutics

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Question
Answer
carbamezepine   Na+ Channel blocker. Side effects are hyponatremia. Metabolized in liver. Give with meals.  
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Phenytoin   Most common. Tonic-Clonic. Na+ Channel blocker. Side effects are lethargy, abnormal movements, confusion, gingival hyperplasia.  
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Lamotrigine   Na+ Channel blocker. Side effects are Steven-Johnson syndrome. Metabolized in liver.  
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Valporate   Na+ Channel blocker. Enhances GABA. Teratogenic. Metabolized in liver.  
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Topiramate   Na+ Channel blocker. Enhances GABA. Side effects are cognitive impairment, weight loss and kidney stones. Metabolized in liver and kidney.  
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Pregabalin   Side effects are ankle edema and weight gain. Metabolized in kidney.  
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Levitiracetam   Side effects are depression and psychiatric issues. Metabolized in kidney.  
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Epilepsy:   Neurological condition which affects the brain and nervous system by causing seizures.  
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Diagnosis of Epilepsy   : EEG or MRI  
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Treatment of Epilepsy   Antiepileptics, Vagus Nerve Stimulation, Surgery  
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Adverse Effects of Epilepsy   N/V/D, sedation, suicidality.  
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Nursing Considerations for Epilepsy   Seizure history, medications, allergies, panic attacks, autonomic nervous system responses, neurological assessment, lab results, skin assessments, oral exam, vital signs, environment assessment, vision.  
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Parkinson’s Disease:   Neurodegenerative disorder that affects movement. Deficit in dopamine.  
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Diagnosis for Parkinson's   Medical history, neurological examination (look for resting tremor, bradykinesia and rigidity) and DaTscan.  
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Treatment for Parkinsons'   Medication, PT, OT, Speech Therapy, deep brain stimulation  
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Carbidopa-levodopa   Levodopa the most effective Parkinson’s med is a natural chemical that passes into your brain and is converted to dopamine. Levodopa is combined with carbidopa which protects levodopa from premature conversion to dopamine outside your brain, which preven  
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Dopamine agonists   don’t change into dopamine like levodopa  
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MAO-B inhibitors   prevent the breakdown of dopamine by inhibiting the brain enzyme B  
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Catechol-O-methyltransferase inhibitors   prolongs the effect of levodopa therapy by blocking an enzyme that breads down dopamine  
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Anticholinergics   helps with tremors, stay away if you are older because of the kidney and liver  
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Amantadine   short term relief of mild, early stage Parkinson’s disease. Symmetrel is also an antiviral.  
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Anxiolytic Drugs   Alrazolam, Diazepam, Lorazepam, BuSpar  
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Contraindications of Anxiolytic drugs   allergy, narrow angle glaucoma, pregnancy.  
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Adverse Effects of anxiolytic drugs   Addictive, sedation  
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Mood Stabilizers   Treats bipolar disorder.  
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Drugs of mood stabilizers   Lithium, anti-epileptics, atypical antipsychotics.  
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Antidepressants first generation Drugs   Tricyclics, Tetracyclics, MAOIs  
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Antidepressants second generation drugs   SSRIs, SNRIs  
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Antipsychotics   Treat serious mental illnesses such as drug-induced psychoses, mania, schizophrenia.  
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Side Effects of Antipsychotics   Sedation, dry mouth, visual disturbances, flushing, constipation, weight gain, tardive dyskinesia.  
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Contraindications of antipsychotics   Allergy, CNS depression, brain damage, kidney/liver disease, blood dyscrasias, uncontrolled epilepsy.  
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First Generation (Typical) of psychoanalytic   Haldol  
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Second Generation (Atypical) of psychoanalytic   Abilify, Clozapine, Risperdal.  
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Nursing considerations of psychoanalytic   No milk with MAOIs! Black box warning for suicidal thoughts.  
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