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biology 12 13 14 rev

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Question
Answer
thymine dimers   pair of abnormally chemically bonded adjacent bases in dna resulting from damage by UV  
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P53 gene   tumor suppressor gene more frequently mutated in human cancers than any gene  
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eukaryote   wrapped around histone molecules to form beaded string  
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onogene   gene that in certain circumstances can transform a cell into a tumor cell  
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mutagens and carcinogens   associated with induced mutations  
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frameshift mutation   deletion of one base pair that alters the sequence of codons  
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posttranscriptional control   level of genetic control that involves the processing of early rna transcripts to mrna and the rate at which mrna leaves the nucleus  
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transcriptional control   most critical level of eukaryotic control  
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xenotransplantation   any procedure that involves the transplantation, implantation, or infusion into a human  
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gene cloning   accomplished by recombinant dna technology and polymerse chain reactions  
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The introduction of normal genes into an afflicted individual for therapeutic use is called   gene therapy  
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bioformatics, proteomics, genomics   field of study would scientists predict a protein and three-dimensional shape and how DNA mutations would affect protein function.  
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5 codon sequences   the number of codon sequences it would require to produce the following amino acid sequence: alanine - proline - serine - isoleucine - stop.  
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anticodon   group of bases on trna that is complementary to a specific mrna codon  
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what takes place during translation   attatchment of ribosome to mrna, binding of 2 trna molecules per ribosome (NOT PRODUCTION OF MRNA)  
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dna   unknown chemical is analyzed and found to conain the bases thymine and guanine  
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If one strand of DNA has the base sequence AAGCAA, the complementary sequence is?   TTCGTT (a)  
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sequence of events in translation   initiation, elongation, termination  
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During DNA replication, which enzyme catalyzes the elongation of new DNA by adding, to the 3' end of the previous nucleotide, new nucleotides that are complementary to a DNA template?   dna polymerse  
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nucleotides contain what   pphosphate group, sugar, nitrogen base (NOT HISTONES)  
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In the Watson and Crick model of DNA, the steps of the ladder are composed of ?   a purine and pyrimidine  
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What isthe universal regulatory mechanism in eukaryotes for controlling gene expression?   all are used (control of genes, mrna, and processing of mrna and polypeptides)  
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Active genes in eukaryotic cells are associated with what other material?   euchromatin (loosly packed chromatin)  
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What is the series of events associated with the formation of cancer?   The proto-oncogenes mutate and become oncogenes which are continuously active. There is also an associated loss of tumor suppressor gene activity allowing uncontrolled growth of cells.  
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Describe xeroderma pigmentosum.   inherited condition characterized by an extreme sensitivity to ultraviolet (UV) rays  
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Describe androgen insensitivity   rare condition that affects the development of a child's genitals and reproductive organs.  
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Define point mutations   change to one or more nucleotides in dna  
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how does gene therapy work   transfer of a specific genetic material (usually DNA) into a patient to treat a particular disease  
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It is estimated that humans have approximately ______ base pairs in our genome.   3 billion  
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transgenic organism   been modified with genetic material from anoter species  
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polymerase chain reaction   used to replicate a fragment of dna and produce large amount of that sequence  
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proteomics   study of protein  
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bioinformatics   science of collecting and analyzing comple bio data  
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genomics   study of genes  
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If a DNA sample contains 13% adenine, what percentage of the sample contains cytosine?   37%  
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success rate of animal cloning   very low (1-3%)  
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When bone marrow stem cells are removed from the patient, infected with a virus that carries a normal gene, and returned to the patient, this is an example of ?   ex vivo gene therapy  
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gene pharming   use of transgenic farm animals to produce pharmicudicals  
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transgenic bacteria   have been given suicide genes that cause them to self-destruct when the job for which they are engineered has been accomplished.  
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