Biochem 2 - 2nd exam
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| what does an increase in acetyl coa do to GNG? why? | Stimulates... inhibits pyruvate DH so pyruvate is more likely to go to GNG
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| Where does Acetyl CoA + OAA ----- citrate take place? | Matrix of mito
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| Citrate ---- CoA + OAA takes place? | cytosol
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| Glycogen gets acted on by glycogen phosphorylase and Pi give you what? | Glucose 1P
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| In glycogen breakdown, glucose 1P is converted to what via what enzyme? Why is it converted to this? | 1. Glucose 6P via phophoglucomustase 2. Because G6P cam then go to glycolysis and make ATP
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| What cycle creates G6P to enter a glycolysis cycle? | Glycogen breakdown... GNG
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| Synthesis of glucose come from non carbohydrate precursors...name them | Lactic acid, amino acids, glycerol
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| Pyruvate carboxilase is located in the ___ of the kidney and liver. | mito
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| Malate shuttle : pyruvate to OAA via what? Where does this occur? | Pyruvate carboxylase...INNER MEMEBRANE OF MITO
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| How does OAA get out of the inner membrane of the mito to the cytosol for PEP carboxikinase to work on it? | Malate shuttle
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| Alpha keta acids enter into krebs and form what? This is a direct precursor to what? | OAA - Pyruvate
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| Substance that makes ketone bodies | Acetyl CoA or things that can make Acetyl CoA
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| 3 things that can turn into Acetyl CoA | Fats through OHOT Citrate through citrate lyase and Pyruvate through pyruvate DH
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| When we are ketotic, what enters the krebs? What spills over? What is made? What will this prevent? | 1. Fatty acids 2. Acetyl CoA 3. Ketone bodies 4. Protein catabolise (amina acid degregation)
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| The overcoming of pyruvate kinse requires 2 steps... where do they take place? | step 1 = Inner membrane of mito in liver Step 2 = Cytosol of liver
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| What does fatty acid synthse do? | CRDR
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| What does Acyl CoA DH do? | OHOT
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| What makes acetyl CoA? | Pyruvate ---PDH--- Acetyl CoA
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| Ketones are primarily created from __ and can be oxidized to make ___? | Fat, ATP
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| What cycle takes lactate, sends it to the liver to make glucose? | Cori Cycle
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| In the morning, what is being tunred into glucose? | Amino acids
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| What cycle takes alanine to the liver and makes glucose? | Glucose - Alanine cycle
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