SSRI
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| Celexa | Citolopram
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| Lexapro | Escitalopram
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| Prozac, Prozac weekly, Sarafem | Fluoxetine
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| Luvox | fluvoxetine, for OCD only
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| Paxil | Paroxetine
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| Zoloft | Sertraline
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| 5HT1, 5HT2, 5HT3 effects | 5HT1: depression, 5HT2-sexual dysfxn, 5HT3-GI SEs.
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| SSRI and Bleeding | 5HT required for Plt aggregation, SSRI incre GI bleeding similar to NSAID, used together incre risk of GI bleeding. Luvox and celexa less bleeding
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| SSRI SEs | Activating(fluoxetine)or sedating(fluvoxetine), GI, Sex dysfxn, HA, Hypo-Na, Anticholinergic (Paroxetine only)
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| Long t1/2 SSRI | Fluoxetine, d/c MAOI 2 weeks prior to fluoxetine, d/c fluoxetine 5 weeks prior to MAOI.
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| Sarafem dose | fluoxetine, start 14 days b4 mens, initial 20mg/d; max 80mg/d
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| Prozac Weekly strength | 90mg ER cap, equal to 20mg QD, dose = 1 cap QW start 7 days after last daily dose of fluoxetine.
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| Prozac weely indication | MDD only
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| fluoxetine indication | MDD, OCD, PMS. Sarafem-PMS, Prozac weekly-MDD
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| Paroxtine strength | Paxil: 10,20,30,40mg. Paxil CR: 12.5, 25, 37.5mg
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| SSRI used for Bulimia nervosa | Fluoxetine
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| Celexa indication | MDD
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| Lexapro indication | MDD, GA
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| Prozac indication | MDD, OCD, PMS, Buli-Nervosa
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| Sarafem indication | PMS
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| Prozac weely | MDD
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| Paxil, Paxil CR | MDD, OCD, PD, SAD, PTSD
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| Zoloft indication | MDD, OCD, PD, PTSD
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| PTSD and PD | Paxil + Zoloft
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| SAD | Paxil, Paxil XR
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| SSRI dose range | Lexapro(10-20), Celexa(10-60), Paroxetine&fluoxetine(10-80), Zoloft (50-200)
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| Only SSRI have solution | Lexapro soln 5mg/5ml.
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| SNRI | Effexor(venlafaxine), Cymbalta(duloxetine), Pristiq(desvenlafaxine), Savella(milnacipran)
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| DN-agonist | Bupropion, not related to 5HT -> not Sex dysfxn.
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| SRI + alpha blocker | trazodone (Desyrel), Nefrazodone (Serzone)
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| Ghost tablets | Venlafaxine ER, Procardia XL, Covera HS
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| For diabetic peripheral neuropathy (fibromyalgia) | Duloxetine (Cymbalta)
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| Duloxetine dose | initial: 30, usual: 60, max 120 (no benefit over 60)
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| Savella indication | fibromyalgia only.
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| 3 dugs approved for fibromyalgia | Lyrica(pregabalin), Cymbalta(duloxetine), Savella(milnacipran)
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| anti-depression & want to incre weight | Remeron(mirtazapine)- increase appetite
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Created by:
thuytaimi