anticoagulation
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| clotting factors inhibited by warfarin | II, VII, IX, X and protein C and S (anticoagulants)
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| half life of factor II | 72 hours
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| half life of factor VII | 6 hours
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| half life of factor IX | 24 hours
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| half life of factor X | 36 hours
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| in acute VTE, how long should you overlap warfarin and LMWH. why is this overlap necessary | 5 days and INR 2+ for 24 hours. do this in order to fully suppress factor II. if not, will have suppressed protein C and S which act as anticoagulants but still have clotting from factor II which leads to a hypercoagulable state.
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| gene mutations associated with warfarin and what they alter | VKORCI - alters warfarin sensitivity
2C9 - alters half life and metabolism
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| warfarin pregnancy category and breastfeeding | preggers category X and ok with breastfeeding
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Created by:
mjuhlin
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