arrhythmias and ACLS
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meds used in the pulseless VT/Vfib algorithm in ACLS | epinephrine 1 mg or vasopressin 40 mg alternate with amiodarone 300 mg x1 f/b 150 mg x1 or lidocaine in a pinch.
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meds used in asystole/PEA algorithm in ACLS | epinephrine 1 mg or vasopressin 40 mg
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meds used in symptomatic bradycardia algorithm in ACLS | atropine 0.5 mg, may repeat Q3-5 mins up to 3 mg. if not effective may try transcutaneous pacing dopamine 2-10 mcg/kg/min or epinephrine 2-10 mcg/min,
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meds used in tachycardia in ACLS. specifically narrow complex with regular ventricular rhythm | typically SVT or sinus tach. use vagal maneuvers or adenosine. 6 mg f/b 12 mg up to two doses. decrease to 3 mg if pt on CBZ or dipyrimadole or post heart transplant. increase dose if pt on theophylline or caffeine
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meds used in tachycardia in ACLS. specifically narrow complex with irregular ventricular rhythm | typically afib or flutter. use rate control. non-DHPs or beta blockers or digoxin.
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meds used in tachycardia in ACLS. specifically wide complex that is VT or of unknown mechanism | adenosine. alternatively can try amiodarone. can use procainamide or sotalol if pt does NOT have prolonged QTc.
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meds used in tachycardia in ACLS. specifically wide complex with confirmed SVT | adenosine
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meds used in tachycardia in ACLS. specifically wide complex with polymorphic VT | typically QTc >500 ms. torsades. if stable use mag 1-2 g boluses. up to 16 g in 24 hours. if unstable defibrillate. correct electrolytes specifically mag and potassium.
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Class Ia antiarrhythmics | Sodium channel blockers. disopyramide, quinidine, procainamide (double quarter pounder) intermediate
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Class Ib antiarrhythmics | Sodium channel blockers. lidocaine, mexilitine, phenytoin (lettuce mayo pickles) fast
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Class Ic antiarrhythmics | Sodium channel blockers. flecainide, propafenone (fries please) slow
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Class II antiarrhythmics | beta blockers - specifically metoprolol, esmolol and atenolol
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Class III antiarrhythmics | potassium channel blockers. amiodarone, dronedarone, dofetilide, sotalol, ibutilide
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Class IV antiarrhythmics | calcium channel blockers. NON DHPS diltiazem, verapamil
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mainstay of therapy for chronic treatment of ventricular arrhythmias | beta blockers. only drug with mortality benefit. amiodarone and sotalol also occ. used but no mortality benefit. typically only for altering threshold of ICD firing.
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Which antiarrhythmics should be avoided in HF pts | Class Ia and Ic (intermediate and slow sodium channel blockers)
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Which antiarrhythmics should be avoided in acute MI pts | Class Ia and Ic (intermediate and slow sodium channel blockers) increases mortality in this population.
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