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Mechanical Ventilation - Unit 2 SPC

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Question
Answer
What is responsive Hypoxemia?   Significant response to increase FIO2. Due to V/Q mismatch. A 20% increase in FIO2 = 10mmHg increase in PaO2  
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What is refractory Hypoxemia?   No increase in PaO2 with increase in FIO2. Due to combo of anatomic and capillary SHUNT  
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What is Deadspace?   Ventilation w/o Perfusion = High V/Q. From Pulmonary Embolism  
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What is Pulmonary/Capillary Shunt?   Perfusion w/o Ventilation = Low V/Q. From ARDS, pneumonia, atelectasis.  
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Normal V/Q?   they should match = 1.0 but normal is 0.8  
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PaO2/FIO2 (PF) ratio   lower is worse. <300 = acute lung injury, <200 = ARDS  
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Normal PaO2/FIO2 (PF) ratio   400  
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Calculate Minute Ventilation   RR X Vt(Tidal V)  
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Calulate VD/VT   (PACO - PECO)/PACO, Normal VD/VT = .30, pt w/Puml. Embolis have higher ratios  
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Calculate Effective Minute Ventilation   VA = (1-VD/VT) x RR x Vt  
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Calculate Static Compliance   Remember Stat = Plat, Vt/(Plat - PEEP if any)  
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Normal Static values   0.05-0.17 L/cmH2O or 50-170ml/cmH2O  
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Static measures what?   Lung Compliance w/o airflow  
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Calculate Dynamic Compliance   Vt/(Peak - PEEP if any)  
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Dynamic measures what?   Airway resistance during airflow  
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Static Compliance is altered by   changes in Lung and Thorcic compliance  
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Dynamic Compliance is altered by   Lung, Thoracic AND AIRWAY Resistance  
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Calculate Airway Resistance   Peak-Plat pressure/Flow  
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Normal Airway Resistance Value   1-2 cmH2O/L/sec, Athsma and Emphysema is 13-18  
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Tissue Resistance   caused by non elastic tissues in contact with Respiratory Tract, i.e. great blood vessels, certain muscles, and some upper ab contents  
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Name the 3 Deadspaces   Anatomical, Alveolar, Mechanical  
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Anatomical Deadspace   Conducting Airways  
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Mechanical Deadspace   Re-breathed gas from Mechanical attachments  
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Alveolar Deadspace   Gas not reaching functioning gas exchange units  
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What alters THORACIC Compliance   Shit that affects the chest wall, Kyphoscoliosis, Pectus Excavatum, Ascites, Obesity, Chest Strapping, Diaphragmic impairment  
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Factor that alter LUNG, THORACIC, STATIC, and DYNAMIC Compliance   Congestion(CHF, Pulmonary Edema), Atelectasis, Fibrosis, Emphysema, Pneumonia  
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Relationship between PACO2 and pH   When starting at PACO2 of 40, for every 20 increase, the pH decreases .10, ... for every PACO2 decrease of 10, pH increases by .10  
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Changes in BiCarb caused by PACO2   for every 10 increase in PACO2, HCO3 increases 1,...for every 10 decrease in PACO2, HCO3 decreases 1.5  
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30 is 60, 60 is 90, and 40 is 75   If PO2 = 30 sat is 60, 60 is 90, and 40 is 75(VENOUS)  
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If suction cath meets resistance...   get tube with smaller diameter.  
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