oxygenation1
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| Oxygen Delivery equals | Blood O2 content x Amount of blood going to the tissue
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| DO2 equation | CaO2 x CO
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| Normal DO2 | 600 - 1000 ml/min
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| CaO2 (Blood O2 content) | (Hg x 1.34 x SaO2)+(PaO2 x 0.003)
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| Factors affecting DO2 in order of importance | CO, Hb, Hb Sat, PaO2
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| Oxygen Index (OI) normal | DO2/BSA = 500-600
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| Two methods of VO2 Oxygen consumption assessment | 1) Indirect calorimetry
2) Fick Equation
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| Fick Equation | V02 = (Ca02-CvO2) x CO
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| Normal VO2 Oxygen consumption | 250 ml/min
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| Normal V02/BSA | 3-4 ml/min/kg
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| Fick Equation Limitation | requires PA catheter and artline
affected by measurement error: thermodilution CO, hb measurement, Sat measurement
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| O2ER is | Oxygen balance comparing O2 transport vs O2 consumption
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| O2ER | V02/D02
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| O2ER | (Ca02-Cv02)/Ca02
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| O2ER 40% range | suggest disturbances in cellular oxygenation
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| SvO2 / mixed venous saturation | estimate of adequancy of balance between O2 transport and O2 consumption
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| PAO2 Alveolar equation | [(PB-PH20)x FiO2)] - (PaCO2/0.8)
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| P(A-a)gradient | PAO2 - PaO2
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| Alveolar Ventilation (VA) | (Vt-VD) x RR OR VE - VD (deadspace vent.)
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| VD.; deadspace ventilation | VD x RR
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| Deadspace volume | Vt x (PaCO2 - PeCO2)/PaCO2
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Created by:
clementine