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oxygenation1

QuestionAnswer
Oxygen Delivery equals Blood O2 content x Amount of blood going to the tissue
DO2 equation CaO2 x CO
Normal DO2 600 - 1000 ml/min
CaO2 (Blood O2 content) (Hg x 1.34 x SaO2)+(PaO2 x 0.003)
Factors affecting DO2 in order of importance CO, Hb, Hb Sat, PaO2
Oxygen Index (OI) normal DO2/BSA = 500-600
Two methods of VO2 Oxygen consumption assessment 1) Indirect calorimetry 2) Fick Equation
Fick Equation V02 = (Ca02-CvO2) x CO
Normal VO2 Oxygen consumption 250 ml/min
Normal V02/BSA 3-4 ml/min/kg
Fick Equation Limitation requires PA catheter and artline affected by measurement error: thermodilution CO, hb measurement, Sat measurement
O2ER is Oxygen balance comparing O2 transport vs O2 consumption
O2ER V02/D02
O2ER (Ca02-Cv02)/Ca02
O2ER 40% range suggest disturbances in cellular oxygenation
SvO2 / mixed venous saturation estimate of adequancy of balance between O2 transport and O2 consumption
PAO2 Alveolar equation [(PB-PH20)x FiO2)] - (PaCO2/0.8)
P(A-a)gradient PAO2 - PaO2
Alveolar Ventilation (VA) (Vt-VD) x RR OR VE - VD (deadspace vent.)
VD.; deadspace ventilation VD x RR
Deadspace volume Vt x (PaCO2 - PeCO2)/PaCO2
Created by: clementine
 

 



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