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Endometrial, Cerbvix CA, Radiation Therapy, Treatment, Fields

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Question
Answer
show cerix (16%), invasive in older group  
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show endometrial 48%  
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show increase  
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What does endometrial present with and what is good about it   show
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What are risk factors of endometrial ca   show
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show rare, mostly older women, vulvar 3 times as common as vaginal risk  
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show pap smear, done via curettage  
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Anatomically what is the cervix   show
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show The cervix is the lower third of the uterus that extends into the apex of the vagina  
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show 4th  
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Of the cancers pertaining to cervix what is the most common   show
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What cancer accounts for 10% of cervix cancers   show
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show Small cell and clear cell types, they also have a higher metastatic potential  
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show external iliac, obturator, and hypogastric (internal iliac) chains.  
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show FIGO staging system  
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show Primary tumor cannot be assessed  
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What in regards to the stage of cervix ca is T0   show
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show Carcinoma in situ, preinvasive carcinoma  
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What is special about stage 0 in regards to FIGO   show
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What in regards to the stage of cervix ca is T1 (FIGO I)   show
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show INvasive carcinoma diagnosed by microscopy. Stromal invasion with a max depth of 5 mm and a horizontal measurment of 7 mm or less. If there is vascular space involvement venous or lymphatic does not affect the classification  
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What do you need to know in regards to the stage of cervix ca is T1a1   show
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What do you need to know in regards to the stage of cervix ca T1a2   show
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What do you need to know in regards to the stage of cervix ca T1b   show
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show Clinically visible lesion 4 cm or less in greatest dimension  
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show Clinically visible lesion more than 4 cm in greatest dimension  
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show Cervical ca invades beyond uterus but not to pelvic wall or to lower third of vagina  
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What do you need to know in regards to the stage of cervix ca T2a   show
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show Clinically visible lesion 4 cm or less in greatest dimension  
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What do you need to know in regards to the stage of cervix ca T2a2   show
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What do you need to know in regards to the stage of cervix ca T2b   show
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show Tumor extends pelvic wall/ causes hydronephrosis or nonfunctioning kidney  
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What do you need to know in regards to the stage of cervix ca T4   show
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show IIIB  
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What does T4 represent in figo staging   show
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show M0 no distant mets, M1 Distant mets (including peritoneal spread, involvement of supraclav, mediastinal, or paraaortic lymph nodes, lung liver or bone)  
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show IVB  
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show Invasive, keratinizing, nonkeratinizing, verrucous  
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show initially a pelvic exam, pap smear, and biopsy of any lesions. To further stage, curettage and dilation under anesthesia to examine uterine involvement is needed, this would be paired with a cbc and urine  
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What has replaced IVP's for staging now   show
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show total abdominal hysterectomy and removal of vaginal cuff.  
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show Tandem and ovoid giving 45 to 55 gy to point a.  
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FOr stage Ia2 what might be used for tx   show
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For stage Ib2 cervical disease, what is used   show
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show irradiation and chemo, unless chemo is contraindicated.  
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show Brachy is important aspect of tx and for control, when brachy is not used survival rates decrease.  
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What is the technique used on a whle pelvis (cervix ca)   show
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What is the lower border for RT with cervix cancer   show
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show at top or bottom of L5 or may be extended upward to l4 for a portion of treatment depending on potential involvement of nodes.  
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show 1.5 to 2 cm lateral to pelvic sidewall in ap/pa plane, ant border of lats may fall beyond pubic symphysis if not at it.  
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show block that includes external iliac nodes and post border including s3  
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if there is ant or post extension what must happen to the fields (cervix ca)   show
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show To decrease dose given to entire rectum and bladder, the four field technique allows you to block the bladder and rectum  
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in regards to positioning what may help with the tx of cervix ca   show
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How is point A prescribed for cervix ca   show
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show 3cm lat to point a  
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What are some of the clinical presentations of endometrial ca   show
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show aspiration curettage is the standard currently, due to the increase of accuracy over pap smears.  
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show women with uterine bleeding have been getting endometrial sampling or aspiration while in the office setting.  
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show aspiration, chest xray, blood count, chemistries, urinalysis and nod surgery is the standard for initial defnitive management. An ultrasound and ct/mri is often being performed first if disease may be beyond uterus.  
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What is most common for endometrial ca   show
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What is seen about 20% of the time in endometrial cancer (type of ca)   show
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What is an extremely malignant form of endometrial ca   show
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show TAH and no other tx  
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show TAH and brachy alone, low doses of 60 to 70 gy used in one application, or high doses of 5 to 7 gy at a 5mm depth in three applications.  
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What is the treatment guideline for endometrial ca stage Ic or higher, grade 3   show
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show Nodal dose of 45-50 gy, and 80 gy to the mucosa  
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For medically inoperable and stage III/Iv endometrial patients what tx alone can be used   show
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For stage IB, grade 1 &2 and sometimes stage Ia, grade 2 what might be used (tx beyond TAH)   show
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show similar to cervical fields, midline blocking used if brachytherapy is included.  
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show fatigue, diarrhea, dermatitis, dysuria  
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show Diarrhea, and is related to large/small bowel treatment. Chemo may significantly worsen problem  
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What can help against diarrhea that patients may experience   show
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What is a side effect more common using low energy beams in treating gynecologic cancers   show
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show Domboro soaks, aquaphor and natural gels/lotions.  
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What side effect may occur in the third or fourth week of pelvic irradiation for gynecologic cancers and how can it be lessened   show
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What can be used to relieve urinary frequency when patient is having dysuria   show
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show Superficial en face radiation using orthovoltage, high-energy photons, or electrons can be applied directly to the vaginal and cervical tumors with large fraction size and not count against the total prescribed dose.  
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show hemorrhoidal preparations, steroids, topical anesthetic agents, and sitz baths  
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show menopause, vaginal dryness/narrowing/shortening, chronic cystitis, proctosigmoiditis, enteritis, and bowel obstruction.  
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What can be done to help late side effects of pelvic irradiation due to gynecologic cancers (vaginal dryness, shrinkage, ulceration)   show
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As a therapist what are some things that can help reproducibility with pelvic irradiation   show
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show Watery diarrhea, which needs to be brought to the staff's attention.  
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show SAD  
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