Reduce or stop the drug
Cardiac pacemeker for heart block
Digitalis antibodies
Arrhythmias may be converted to normal sinus rhythm by K+
Antiarrhythmic drugs, such as lidocaine, phenytoin, procainamide, or propranolol, used when K+ conc is high
What is the therapeutic value of ACEIs?
DOC in HF
No tolerance
Retard progression of HF
Decrease arrhythmias
Only drugs which decrease mortality, but only when the highest tolerated doses are used
What are the causes of diuretic resistance in HF?
Noncompliance with regimen
Excess dietary Na+ intake
Decreased renal perfusion and GFR
Selective reduction in glomerular perfusion pressure following initiation of ACEI therapy
NSAIDs
Primary renal pathology
Reduced or impaired diuretic absorption
Nonselective a-adrenergic antagonists used for vasodilators:
Phentolamine
Examples of phosphodiesterase inhibitors (which are cAMP dependent agents):