Question | Answer |
True or False? Aminoglycosides are given orally. | False-poor intestinal absorption |
Gentamicin, kanamycin, neomycin, streptomycin, tobramycin are all ___ ____. | Natural Aminoglycosides |
Amikacin and Netilmicin are ____ ____. | Semisynthetic Aminoglycosides |
What are the three commonly used Aminoglycosides? | Gentamicin, Tobramycin, and Amikacin |
Sides effects of Aminoglycosides include ____ and ______. | nephrotoxicity and ototoxicity |
The lowest concentration of a drug needed to kill a certain standard amount of bacteria? | Minimum Inhibitory concentration |
You give Aminoglycosides in once-daily dosing because of ____ _____ _____. | Concentration dependent kill |
With Aminoglycosides, troughs above ___ are associated with ototoxicity and nephrotoxicity | 2 mcg/ml |
What should a nurse be sure to measure after administering Aminoglycosides? | Peak and Trough |
ototoxicity damages what cranial nerve? | eighth |
Nurses should monitor what lab values for adverse effect of Aminoglycosides? | BUN and Serum Creatine Levels |
Aminoglycosides bind to what and prevents what? | ribosomes and protein synthesis |
Babies born with poop on them usually recieve what two antibiotics? | Gentamicin and Ampicillin |
What are the peak levels for Aminoglycosides? | 4-10mcg/ml |
What are the trough levels for Aminoglycosides? | 1-2mcg/ml |
Patient comes in with symptoms of tinnitus, n/v, dizziness, and rashes. He has just informed you he has been taking some antibiotic. which is likely an? | aminoglycoside |