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NAPLEX 28 (HTN)
HYPERTENSION
| Question | Answer |
|---|---|
| T/F: BB are first line for CAD? | False. BB are not first line for CAD prevention |
| JNC goal for HTN?; If pts have diabetes or CKD | <140/90mmhg; diabetes & ckd (<130/80) |
| recommended daily Na intake for pts with HTN? | <1.5G/DAY (NORMAL: <2.4g/day) |
| Thiazides vs. loop: which is recommended for CrCl<30ml/min | loop |
| Thiazides vs. loop:decreases Ca and Cl? | loop |
| Thiazides vs. loop:causes more of ototoxicity (which medication of that drug class has more often) | loop; Edecrin (ethacrynic acid) |
| Thiazides vs. loop:hyperglycemia? | both |
| potency of loops: lasix, bumex, demadex | bumex 1mg, demadex 20mg, lasix 40mg |
| microzide? MOA? | hydrochlorothiazide; thiazide |
| Zaroxolyn... MOA? | thiazide... Metalozone |
| which thiazide ok in reduced renal function | metolazone |
| thialitone? | chlorthialidone |
| brand/generic: diuril | chlorithiazide |
| lozol... MOA? | indapamide... thiazide |
| brand/generic: EDECRIN | ethacrynic acid |
| brand/generic: Torsemide | Demadex |
| brand/generic: Maxide | Triamterene + HCTZ |
| brand/generic: Aldactone | sprinolactone |
| which K sparing has increase S/E of gynecomastia, breast tenderness? | sprinolactone |
| What are the contraindications to K sparing meds? | anuria, K>5.5, CrCl<30ml/min |
| brand/generic: Inspra | Eperlerone |
| Midamor... MOA? | K sparing (Amiloride) |
| brand/generic: Diovan | valsartan |
| brand/generic: Cozaar | losartan |
| brand/generic: Avapro | ibrasartan |
| brand/generic: Benicar | olmesartan |
| brand/generic: Micardis | Telmisartan |
| Contraindication of ACEI/ARBs | don't use in renal artery stenosis; Angioedema; DC ASAP when pregnant |
| brand/generic: Lotensin | benazepril |
| vasotec | enalapril |
| enalaprilat- dosage form | IV enalapril |
| prinvil, zestril | lisinopril |
| accupril | quinapril |
| brand/generic: Altace | ramipril |
| brand/generic: capoten | captopril |
| brand/generic: Monopril...MOA? | Fosinopril |
| Drug class: Aceon | Perindopril.. ACEI |
| Drug class: Mavik | ACEI... Trandolapril |
| brand/generic: Tekturna | Aliskiren |
| Combo brand/generic: Lotril | ACEI/CCB: AMLODIPINE + BENAZEPRIL |
| Combo brand/generic: Lotensin HCT | hydrochlorothiazide + benazepril |
| Combo brand/generic: Exforge | ARB/CCB: Amlodipine + Telmisartan |
| Combo brand/generic: AZOR | amlodipine + Olmesartan |
| Combo brand/generic: Avalide | irbesartan + HCTZ |
| Combo brand/generic: Hyzaar | Losartan + HCTZ |
| Combo brand/generic: MICARDIS HCT | Telmisartan + HCTZ |
| Combo brand/generic: DIOVAN HCT | Valsartan + HCTZ |
| Combo brand/generic: BENICAR HCT | OLMESARTAN + HCTZ |
| Combo brand/generic: Tenoretic | ATENOLOL + CHLORTHALIDONE |
| Combo brand/generic: Ziac | BISOPROLOL + HCTZ |
| Combo brand/generic: Dyazide, Maxide | TRIAMTERENE + HCTZ |
| brand/generic: tenormin | atenlol |
| brand/generic: lopressor | metoprolol tartrate |
| zebeta... moa? | bisoprolol...b-blocker |
| brand/generic: Bystolic | Nebivolol |
| MOA & brand/generic: Inderal | propanlol; non-specific BB |
| MOA: Cartrol | non-specific BB |
| ISA agents of BB (agents that dont decrease HR) | CAPP; Acebutolol, Carteolol, Penbutolol, Pindolol |
| MOA & brand/generic: Blocardren | non-spec BB; Timolol |
| MOA & brand/generic: Coreg, Coreg CR take with food or empty stomach? | Non-spec alpha & Beta; Carvedilol |
| MOA & brand/generic: Trandate | non-spec alpha & beta; Labetalol |
| MOA & brand/generic: Normodyn | non-spec alpha β Labetalol |
| Medications for Pregnant hypertensive pts? | labetolol, methyldopa, nifedipine |
| MOA & brand/generic: Hytrin | alpha-blocker (vasodilation); terazosin |
| MOA & brand/generic: Cardura | alpha-blocker (vasodilation); doxazosin |
| MOA & brand/generic: norvasc | amlodipine |
| MOA & brand/generic: Plendil | Felodipine |
| MOA & brand/generic: Aldalact CC | nifedipine |
| MOA & brand/generic:Procardia XL, Procardia | Nifedipine |
| MOA & brand/generic:AFEDItab | Nifedipine |
| common side effect to DHP that's different from NDHP? | peripheral edema; reflex tacchycardia |
| T/F: for immediate reflief of BP, SL nifedipine is recommended? | FALSE!!! Do NOT USE SL NIFEDIPINE; increased risk of MI |
| inpatient DHP: CLEVIPREX; what diet restriction? | Clevipine (IV only); containes ~20% lipids (do not use in SOY ALL |
| DHP: are CYP ____ INHIBITORS and CYP ___ subtrates | cyp3A4 |
| MOA & brand/generic:Catapress | Clonidine |
| MOA & brand/generic:Catapress Patch | patch; applied weekly |
| MOA & brand/generic:Tenex | Guanfacine |
| MOA & brand/generic: Aldomet | Methyldopa |
| Side effects to Apresoline? | hydralazine; Lupus like syndrome (dose,duration related); report fever, joint/muscleaches, fatique, reflex tacchycardia |
| Difference btwn hypertensive emergency vs. urgency? | BP>185/110 +/- organ failure |
| Treatment rec for HTN urgencies: (fast onset) | catopril (capoten), clonidine (captapress), labetalol (normodyne, trandate) |
| NITROGLYCERIN: storage in glass or plastic? why? | store in glass; absorption into plastic |
Created by:
tang4884