Help
Options
Question
ADA goal for AIC
click to flip
Didn't know it?
click below
click below
Knew it?
click below
click below
Don't know
Question
goal estimated average glucose
Remaining cards (46)
Know
retry
shuffle
restart
0:00
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
NAPLEX-20 (Diabetes)
Diabetes
| Question | Answer |
|---|---|
| ADA goal for AIC | <7% |
| goal estimated average glucose | <154 mg/dl |
| preprandial blood glucose | 70-130 mg/dl |
| how frequent urine test for albumin | annual |
| aspirin therapy for prevention for what age group | men >50yo, female >60 age |
| Glucovance | metformin + glyburide |
| actoplus Met | pioglitazone + metformin |
| Janumet | sitagliptin + metformin |
| Glumetza | Metformin |
| Fortamet | metformin |
| glucophage | metformin |
| contraindication of metformin | scr>1.5 (male), >1.4 (female) or CrCl <60ml/min |
| caution and bbw for metformin | caution with HF, bbw- lactic acidosis |
| metformin ER rec to be taken daily of when in the day? | daily at evening |
| Glumetza and Fortamet - counseling point of seeing medicine in the stool | glumetza-shell of medicine in stoll fortamet- looks like a lumpy tablet in the stool not a problem... medicine has been absorbed |
| Sulfonylureas SHOULD NOT be used with what other antidiabetic drug class d/t to similar MOA? | MEGITINIDES (secreatogues) |
| Diabinese | Chlorpropamide - older agent. not used anymore d/t long duration and risk for hypoglycemia |
| Glucotrol, Glucotrol XL | Glipizide |
| Amaryl | Glimpiride |
| Diabeta | Glyburide |
| Micronase. Which has better absorption? | micronized has better absorption. Glyburide |
| What two drug classes are not recommended for use by ADA d/t long-lasting hypoglycemia? | Diabinese (Chlorpropamide) and (Diabeta, Micronase) Glyburide *partially active metabolite that can accumulate in renal dysfxn (CrCl<50) |
| Prandin | Meglitinides |
| actos | pioglitazone |
| Duetact | Pioglitazone + Glimepirmide (Amaryl) = Duetact |
| Avandia | Rosiglitazone |
| MOA of TZDs? Which TZDs are better for lipids? | pioglitazone; increase insulin sensitivity |
| Common S/E to TZDs? | Hepatic & Cardiovascular risk |
| Which drug class may take several weeks to see results of blood sugar lowering? | TZDs |
| Precose. MOA? | Acarbose. MOA: inhibit alpha-glucosidase in the intestine and amylase in the pancreas- delayed absorption of glucose. inhibit metabolism of sucrose to glucose and frutose |
| T/F: Titrate Acarbose (Precose) & Miglitol (Glyset) should be titrated slowly d/t GI effects | True |
| What is the advantage of using alpha-glucosidase inhibitors? | increase HDL, decrease TG and total cholesterol & don't cause weight gain! |
| Which med class can't lower blood sugar themselves? | Alpha-glucosidase inhibitor |
| If you get low blood sugar with alpha-glucosidase inhibitors, you can't treat hypoglycemia with sucrose form of sugar | True. |
| januvia | sitagliptin |
| Juvisync | sitagliptin + simvastatin |
| side effects to januvia | - nasopharyngitis, upper respiratory tract infections, peripheral edema, rash, hypoglycemia - weight neutral |
| what are incretin enhancers vs. incretin mimetics? | DPP4 inhibitors and GLP-1 agonists (extenidtide-byetta; victoza -liraglutide) |
| Byetta (class?) | Exenatide |
| (class?) Liraglutide | victoza |
| Primary side effect to Byetta? Top S/e involves? Should be avoided in... | Exenatide- NAUSEA * note: other known side effects: PANCREATITIS, RENAL (AVOID IN SEVERE IMPAIRMENT CrCl <30ml/min) |
| Which med requires a MedGuide? Should not be used in a special patient population? | dont use in pts with hx of pancreatitis, gallstones, alcoholism, or high TGs (REQUIRES MedGuide!!!) avoid in severe renal impairment |
| Symlin (generic, class) | Pramlintide |
| Unique use of Symlin? Comes in two different dosage form | Pramlintide (amylinomimetic)- mimics the hormone that mangages post-prandial glucose SymlinPen 120 (Type 2) SymlinPen 60 (Type 1) * can be use in BOTH TYPE 1 AND 2 DM |
| common s/e to Symlin? | - hypoglycemia - nausea - anorexia (d/t preventing glucagon increase) |
| There's a diet restriction when using Pramlintide. what is it? | Only use if you consumed > or equal 250 kcal or >or equal 30grams of carbohydrates/day |
| What Bile-acid binding resin may possibly help with glycemic control? | - Colesevelam (Welchol) |
Created by:
tang4884