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Micro Exam 5
| Question | Answer |
|---|---|
| An invasion or colonization of the body by potentially pathogenic microorganisms. | Infection |
| The cause of a disease? | Etiology |
| A change from a state of health, in which the body is not properly adjusted or capable of performing its normal functions: | Disease |
| The manner in which disease develops | Pathogenesis |
| One organism is benefited at the expense of another? | Parasitism |
| The general relationship between the normal microbiota and the host | Symbiosis |
| One of the organisms is benefted and the other unaffected | Commensalism |
| A symbiosis that benefits both organsims | mutualism |
| Live bacteria cultures intended to exert a beneficial effect | Probiotics |
| Chemicals administered to promote probiotic growth | prebiotics |
| First mild symptoms appear: | Prodromal period |
| The individual regains strength, and the body returns to its prediseased state | Period of convalescence |
| The time between infection and the first appearance of signs and symptoms | Period of incubation |
| The period of time when signs and symptoms subside | Period of decline |
| During this time overt symptoms of the disease are apparent | Period of illness |
| Easily spread from one person to another person | contagious |
| Diseases spread directly or indirectly from one host to another | Communicable |
| Can only be introduced into the body by contamination, such as a wound | Non-communicable |
| An inanimate object that may transmit disease | Fomite |
| A group of symptoms associated with disease | Syndrome |
| Identification of disease | Diagnosis |
| Objective changes caused by a disease that physician may observe | Signs |
| An arthropod, for example, that carries malaria | Vector |
| A toxic, inflammatory condition arising from the spread of bacteria or bacterial toxins from a focus of infection. | Sepsis |
| The presence of bacteria in the blood is known as | bacteremia |
| Sepsis that results from proliferation of bacterial pathogens in the bloodstream | septicemia |
| The presence of toxins in the blood | toxemia |
| The presence of viruses in the blood | viremia |
| People who transmit disease, but do not exhibit any symptoms of illness? | carriers |
| Adisease the occurs only occasionally? | Sporadic |
| Disease acquired in a hospital | Nosocomial |
| Diseases that occur in animals and can be transmitted to humans | Zoonoses |
| The science that deals with the transmission of diseases in the human population, and where and when they occur, is called; | epidemiology |
| In ___ transmission of disease, an isect such as a fly carries the pathogen on its body to human food | mechanical |
| The ___ of a disease is the fraction of the population that contracts it during a particular period of time. | icidence |
| ___ disease is one that develops rapidly but lasts only a short time. | Acute |
| ___ infection is one caused by an oppertunist after the primary infection has weakened the body's defenses | Secondary |
| ___are changes in body function felt by the patient and subjective in nature, such as pain. | Symptoms |
| An abscess is an example of a ___ type of infection. | local |
| An infection in which microorganiisms or thier products are spread throughtout in the body in the blood or lymphatic system is known as ___ infection. | systemic |
| An inapparent, or ___, disease is one that does not cause any noticeable illness. | subclinical |
| the ___ of a disease is the fraction of the population having the disease at a given time. | prevalence |
| Disease intermediate between acute and chronic are described as: | subacute |
| Produced by some members of the genus "Staphylococcus"; forms a fibrin clot around the bacterium | Coagulase |
| A substance produced by some bacteria that destroys certain phagocytic cells: | leukocidins |
| Enzymes that causes lysis of red blood cells: | hemolysins |
| Enzymes that break down fibrin and desolve clots | Kinases |
| The fibrinolysins produced by the streptococci | Kinases |
| May cause hallucinations or gangrene. | Ergot |
| Virulence factor that improves adherence of Neisseria gonorrhoeae | opa |
| Tumor necrosis factor | Cahectin |
| Proteins secreted by bacterium | exotoxins |
| The tetanus toxin is a good exmple of: | Exotoxin |
| A liopolysaccharide component of the cell wall of many gram-negative bacteria | Endotoxin |
| Released upon lysis of the cell; | Endotoxin |
| detected by "Limulus ameobocyte lysate assay" | Endotoxin |
| The capacity ot form toxins | toxigenicity |
| Provides immunity to exotoxins | antitoxin |
| The presence of a toxin in the bloodstream | Toxemia |
| A way to measure virulence | LD50 |
| the degree of pathogenicity | Virulence |
| the ability of a pathogen to cauyse disease in a host | pathogenicity |
| Confers some resistance to phagocytosis | Capsule |
| Entrance through skin and mucous membrane to gain access to body tissue | parenteral |
| very large multinucleated cells caused by viral infection | syncytia |
| An important component of the cell's cytoskeleton that aids in enterance of pathogens into the cell | actin |
| produced by virus-infected cells; helps prevent infection of uninfected neighboring cells | Interferons |
| portion of the outer wall of gram-negative bacterium that is the exotoxin | Lipid A |
| Formerly called endogenous pyrogen | interleukin-1 |
| membrane-disrupting toxin such as a leukocidin | Streptolysin O |
| Staphlococcal toxic shock syndrome caused by superantigens. | Type I toxin |
| An example is diphtheria toxin, which inhibits protein synthesis and kills the cell. | Type III toxin |
| An example is the cell-lysing exotoxin of Staphylococcus | Type II toxin |
| The term LD50 refers to the dose of pathogen that will kill half of the test ___. | animals |
| Hyaluronidase is an enzyme secreted by certain bacteria that digests ___ acid. | hyaluronic acid |
| A dissease associated with ___ -toxins is septic shock | endo-toxins |
| The "Limulus ameobocyte lysate assay is intended to detect | endotoxins |
| One effect of viral infection is unregulated cell growth due to loss of ___ inhibition. | contact inhibition |
| Contributing to invasiveness by "Streptococcus pyogenes" is a cell protein called ___ protein. | M |
| With few exceptions, microorganisms cannot penetrate unbroken skin; however, some fungi grow on the ___ component of the skin. | karatin |
| The avenue by which a microorganism gains access to the body is called its | portal of entry |
| if the pathogen causes a nonfatal disease, the equivalent to the LD50 test is referrred to as ___ (inefective dose) | ID50 |
| the toxin ergot is contained in resistant mycelia called | Sclerotia |
| A microbe is pathogenic only if its characteristics are changed due to a prophage. this is called ___. | lysogenic conversion |
| The study of disease | Pathology |
| The study of the cause of a disease | Etiology |
| The development of disease | Pathogenesis |
| Colonization of the body by pathogens | Infection |
| An abnormal state in which the body is not functioning normally | Disease |
| ___ microbiota may be present for days, weeks, or months | Transient |
| ___ microbiota permanently colonize the host | Normal |
| ___ is the relationship between normal microbiota and the host | Symbiosis |
| ___ ___ is a competition between microbes. | Microbial antagonism |
| Normal microbiota protect the host by | Occupying niches that pathogens might occupy---Producing acids---Producing bacteriocins |
| Live microbes applied to or ingested into the body, intended to exert a beneficial effect | Probiotics |
| ___ ___ are used to prove the cause of an infectious disease | Koch's postulate |
| ___ disease: A disease that is spread from one host to another | Comminicable |
| ___ disease: A disease that is easily spread from one host to another | Contagious |
| Disease that occurs occasionally in a population | Sporadic Disease |
| Disease constantly present in a population | Endemic disease |
| Disease acquired by many hosts in a given area in a short time | Epidemic disease |
| Worldwide epidemic | Pandemic disease |
| Immunity in most of a population | Herd immunity |
| Disease with a period of no symptoms when the causative agent is inactive | Latent disease |
| Systemic infection that began as a local infection | Focal infection |
| Acute infection that causes the initial illness | Primary infection |
| Opportunistic infection after a primary (predisposing) infection | Secondary infection |
| No noticeable signs or symptoms (inapparent infection) | Subclinical disease |
| What predisposing factors make a person more susceptible to disease; | Short urethra in females Inherited traits, such as the sickle cell gene Climate and weather Fatigue Age Lifestyle Chemotherapy |
| Requires close association between infected and susceptible host | Direct Contact |
| Spread by fomites | Indirect Contact |
| Transmission by an inanimate reservoir (food, water, air) | Vehicle Transmission |
| ___ transmission: Arthropod carries pathogen on feet | Mechanical |
| ___ transmission: Pathogen reproduces in vector | Biological |
| Affect 5–15% of all hospital patients | Nosocomial infections |
| Most common Nosocomial infection is; | UTI |
| The study of where and when diseases occur | Epidemiology |
| Incidence of a specific notifiable disease | Morbidity |
| Deaths from notifiable diseases | Mortality |
| Number of people affected in relation to the total population in a given time period | Morbidity rate |
| Number of deaths from a disease in relation to the population in a given time | Mortality rate |
| The same pathogen must be present in every case of the disease | Step 1 of the Koch Postulate |
| The pathogen must be isolated from the diseased host and grown in pure culture | Step 2 of the Koch postules |
| The pathogen from the pure culture must cause the disease when it is inoculated into a healthy, susceptible lab animal | Step 3 of the Koch Postulates |
| The pathogen must be isolated from the inoculated animal and must be shown to be the original pathogen | Step 4 of the Koch Postulate |