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Synap Trans of Excit

Chemical Synaptic Transmission of Excitation

Nerve impulse depolarizes nerve terminal Step 1
Opening of voltage-operated Ca++ channels Step 2
Exocytosis of ACh into synaptic cleft Step 3
ACh diffuses across synaptic cleft Step 4
ACh binds to receptors on upper portion of junctional folds of end-plate Step 5
Rapid increase in permeability of Na+ Step 6
End-plate potential creates local circuit currents Step 7
Action potential propagated throughout muscle fiber Step 8
Created by: jemstotz