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med chem pkas

QuestionAnswer
Amino acid amine 9
amino acid carboxylic acid 2
carboxlyic acid 4-5, withdrawing groups lower
alcohol 17, withdrawing groups lower
NH4+ 9.2, adding methyls raises
Ph-NH3+ 4.6, stabilization by benzene
NH3 38
amide 15
pyridine 5 (benzene with 1 N on ring)
imidazole 6 (5 C ring with 2 N on ring - histidine)
R-SH 8 (better than alcohol because S is bigger to stabilize)
guanine residue 12.5-13
sp3 50
sp2 40
sp 25 - more s character,
Created by: HugsAndKisses
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