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Packrat Review

Heme

QuestionAnswer
Polycythemia Vera presents how? Tx? elevated hemoglobin and hematocrit. On physical examination plethora, engorged retinal veins, and splenomegaly are common. Tx:Phlebotomy
Cheilosis (angular stomatitis)is noted in what type of anemia? iron deficiency anemia
Decreased vibratory sense is noted in what deficency? B12
Hereditary spherocytosis presents how? normocytic, normochromic anemia and many spherocytes.
Dx mod to confirm spherocytosis? osmotic fragility test
Iron deficiency anemia is diagnosed how? Serum Ferritin
G-6-PD deficiency presents how on the RBC? With minimal or no RBC morphologic abnormalities.
How is G-6-PD deficiency diagnosed? measuring G-6-PD enzyme activity level.
Acute myelogenous leukemia presents how? With pancytopenia
A patient with multiple myeloma should be immunized against what pathogen? S. Pneumoniae, H. Flu
Why is it important that a person with MONO avoid contact sports? They present with splenomegaly which increases risk of splenic rupture.
Hemophilia A presents commonly how and is treated with ? hemarthrosis. factor VIII concentrate or cryoprecipitate.
Desmopressin acetate is indicated in what heme diso? von Willebrand's disease
Abnormalities in spectrin and actin are noted in hereditary heme diso? spherocytosis.
Cold agglutinin disease presents how and what finding in blood confirms this dx? with mottled and numb fingers after repeated cold exposure. CBC reveals a mild anemia and Rouleaux.
Chilblains are found on the skin and look like? and are d/t? red, itching skin blistered/inflamed lesions precipated by cold temperatures.
The findings of target cells on the peripheral blood smear indicate what type of pathology and what following test is needed? hemoglobinopathy. Electrophoresis
In HIV-infected females prophylaxis for mycobacterium avium complex (myco=fungus) should be initiated when the CD4 count is less than what value? 75
Giving folate for a macrocytic anemia without treating vitamin B12 deficiency may lead to ? irreversible neurological complications.
Quickest way to lower (thicken the blood) an INR level? give fresh frozen platelets.
what is protamine good for? neutralizing HEPARIN not Cumadin
Mother Rh-negative and a father who is Rh-positive presents with risk of what disease in the newborn? Hemolytic Dz of Newborn. If an Rh-negative woman carries an Rh-positive fetus, she may develop antibodies against Rh when fetal blood cells enter her circulation
Hydroxycholorquine is an oxidative drug that can cause hemolytic Anemia. What Heme Dz is suseptible to oxidative drugs? G6PD. G6PD Assay is the Dx Test of Choice. G6PD is an enzyme deficency found commonly in africans
On peripheral smear what finding is suggestive of G6PD Dz? Bite Cells
CML patients present with what specific organ being affected? Splenomegaly but no enlarged lymph nodes. The spleen really is one big lymph node in essence.
Created by: adamgarling
 

 



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