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pht 100

chapter 8 part 3

it's illegal to compound commercially available products
a counter balance is a 2-pan balance used for larger weights (up to 5kg), has a sensitivity requiremetn in the range of +/- 100mg, & are used for bulk materials (not for compounding)
ingredients & weights should be placed on paper in C3 rx balancing
a C3 balance is also known as a "class a" balance
weighing paper is for avoiding contact between the tray & the ingredients
weighing paper is also called powder paper
a digital electronic balance has a single pan, it's easy to use, it's more accurate & expensive ($2,500+)
digital electronic analytical balances have a capacity of 100g & sensitivity as low as +/- 1mg
the balances have polished brass with noncorrosive coating with both metric & apothecary weights
forceps are used to grasp small objects to avoid hands natural oils which can change weight of objects
hard rubber spatulas are often used for corrosive material
a plate is made of ground glass that mixes compounds
parchment paper can be used if nonabsorbent
mortar & pestle can be made of corse grained porcelain or "wedwood" used for pulverizing
smooth glass mortar & pestles are for liquids & semisolids
a compounding slab is also called an "ointment slab"
cylinders, pipettes, & beakers can be glass or polypropylene
a conical cylinders is wide topped & narrow based or cylindrical
conicals are metric & apothecary
cylinders are calibrated in metric units (more accurate)
beakers are less accurate than cylinders and measure large liquid volumes when precision isn't necessary
pipettes measure liquids less than 1.5mL
hoods, masks, & gowns are used when preparing powders
there are capsule machines & tablet presses
autoclaves sterilize instruments
incubators culture products
minimum compounding requirements are hairnets, lab coats, & gloves
hazard requirements are goggles, masks, double gowns, & eyewashe stations
usp chpt. 795 specifies to wash hands first, to dispose gloves after, & keep food out of the staging area
electronical balances are prefered, must be perfectly leveled, warmed & calibrated up for use, locked when not used, & cleaned afterwards
C3 rx balance is enough for occasional use
measurement error is expected sometimes
allowances are made for some %age errors
%age error formula is error amount/desired amountX100
error %age is an acceptable range of variations over/under measurement
must work within an acceptable error range
use the smallest device that holds the required volume & measure at eye level at the bottom of the meniscus
the meniscus is the moon-shaped/concave liquid appearance in a cylinder
to compound, techs should get a master control record, ingredients, equipment, & mixing directions
most have uninterrupted adequate time
master control record or pharmacists can give the best mixing techniques
comminution is the process of reducing things to fine particles
trituration rubs or grinds things to get fine particles like with mortar and pestle
Created by: wildap