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neuro pharm simple
neuro pharm
| Question | Answer |
|---|---|
| diazepam (valium) benzodiazepine | |
| triazolam (halcion) benzodiazepine | |
| zolpidem (Ambien) | NBRA (non-benzo hypnotic) |
| eszopiclone (lunesta) | NBRA (non-benzo hypnotic) |
| flumazenil | benzodiazepine antagonist |
| disulfiram (antabuse) | blocks aldehyde DH |
| acamprosate (compral) | inhibits NMDARs (prevent glutamate toxicity); treat alcohol w/drawal |
| baclofen | GABA(B) agonist |
| β-carboline carboxyethyl ester | inverse benzo agonist |
| fomepizole | alcohol DH inhibitor |
| phenelzine | MAOI |
| tranylcypromine | MAOI |
| selegiline | MAOI |
| moclobemide | MAOI |
| amitriptyline | TCA |
| nortriptyline | TCA |
| desipramine | TCA |
| clomipramine | TCA |
| imipramine | TCA |
| protriptyline | TCA |
| doxepin | TCA |
| fluoxetine | SSRI |
| sertraline | SSRI |
| citalopram | SSRI |
| escitalopram | SSRI |
| paroxetine | SSRI |
| venlafaxine | SNRI |
| desvenlafaxine | SNRI |
| duloxetine | SNRI |
| buproprion | atypical antidepressant |
| mirtazipine | atypical antidepressant |
| trazadone | atypical antidepressant |
| Vilazodone | atypical antidepressant |
| Nefazodone | atypical antidepressant |
| Lithium | treat bipolar disorder, unipolar depression augmentation |
| chlorpromazine | phenothiazine antipsychotic; low potency block D2R |
| perphenizine | thioxanthene antipsychotic; mid potency block D2R |
| haloperidol | butyrophenone antipsychotic; high potency block D2R |
| Risperidone | atypical antipsychotic |
| Palliperidone | atypical antipsychotic |
| Ziprasidone | atypical antipsychotic |
| Olanzapine | atypical antipsychotic |
| Clozapine | atypical antipsychotic |
| Quetiapine | atypical antipsychotic |
| Aripiprazole | atypical antipsychotic; D2R & 5HT1aR partial agonist & 5HT2a R inhibitor |
| morphine | strong opioid R agonist |
| methadone | strong opioid R agonist |
| meperidine | strong opioid R agonist |
| fentanyl | strong opioid R agonist |
| oxycodone | strong opioid R agonist |
| heroin | strong opioid R agonist |
| codeine | moderate opioid R agonist |
| propoxyphene | moderate opioid R agonist |
| hydroxycodone | moderate opioid R agonist |
| pentazocine | mixed opioid R agonist/antagonist |
| buprenorphine | partial opioid R agonist |
| tramadol | opioid R partial agonist, inhibit 5HT & NE reuptake |
| naloxone | opioid R antagonist |
| naltrexone | opioid R antagonist; decreases rewarding effects of alcohol |
| marijuana | endocannabinoid R agonist |
| ketamine | NMDA R antagonist , dissociative analgesic |
| phenycyclidine (PCP) | NMDA R antagonist , dissociative analgesic |
| MDMA (ecstasy) | complex effects on monoamines |
| methylxanthines (caffeine, theophylline, theobromine) | phosphodiesterase inhibition and adenosine R antagonism |
| nicotine | nicotinic cholinergic R agonist |
| cocaine | CNS blockade of monoamine transport, esp DA & NE, prolonging catecholamine effects; peripheral Na channel inhibition |
| amphetamine | indirect agonist enhancing catecholamine release |
| methylphenidate | amphetamine, decreases DA reuptake by inhibiting DAT |
| dextroamphetamine | indirect agonist enhancing catecholamine release |
| varenicline | partial nicotinic cholinergic R agonist |