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neuro pharm simple
neuro pharm
Question | Answer |
---|---|
diazepam (valium) benzodiazepine | |
triazolam (halcion) benzodiazepine | |
zolpidem (Ambien) | NBRA (non-benzo hypnotic) |
eszopiclone (lunesta) | NBRA (non-benzo hypnotic) |
flumazenil | benzodiazepine antagonist |
disulfiram (antabuse) | blocks aldehyde DH |
acamprosate (compral) | inhibits NMDARs (prevent glutamate toxicity); treat alcohol w/drawal |
baclofen | GABA(B) agonist |
β-carboline carboxyethyl ester | inverse benzo agonist |
fomepizole | alcohol DH inhibitor |
phenelzine | MAOI |
tranylcypromine | MAOI |
selegiline | MAOI |
moclobemide | MAOI |
amitriptyline | TCA |
nortriptyline | TCA |
desipramine | TCA |
clomipramine | TCA |
imipramine | TCA |
protriptyline | TCA |
doxepin | TCA |
fluoxetine | SSRI |
sertraline | SSRI |
citalopram | SSRI |
escitalopram | SSRI |
paroxetine | SSRI |
venlafaxine | SNRI |
desvenlafaxine | SNRI |
duloxetine | SNRI |
buproprion | atypical antidepressant |
mirtazipine | atypical antidepressant |
trazadone | atypical antidepressant |
Vilazodone | atypical antidepressant |
Nefazodone | atypical antidepressant |
Lithium | treat bipolar disorder, unipolar depression augmentation |
chlorpromazine | phenothiazine antipsychotic; low potency block D2R |
perphenizine | thioxanthene antipsychotic; mid potency block D2R |
haloperidol | butyrophenone antipsychotic; high potency block D2R |
Risperidone | atypical antipsychotic |
Palliperidone | atypical antipsychotic |
Ziprasidone | atypical antipsychotic |
Olanzapine | atypical antipsychotic |
Clozapine | atypical antipsychotic |
Quetiapine | atypical antipsychotic |
Aripiprazole | atypical antipsychotic; D2R & 5HT1aR partial agonist & 5HT2a R inhibitor |
morphine | strong opioid R agonist |
methadone | strong opioid R agonist |
meperidine | strong opioid R agonist |
fentanyl | strong opioid R agonist |
oxycodone | strong opioid R agonist |
heroin | strong opioid R agonist |
codeine | moderate opioid R agonist |
propoxyphene | moderate opioid R agonist |
hydroxycodone | moderate opioid R agonist |
pentazocine | mixed opioid R agonist/antagonist |
buprenorphine | partial opioid R agonist |
tramadol | opioid R partial agonist, inhibit 5HT & NE reuptake |
naloxone | opioid R antagonist |
naltrexone | opioid R antagonist; decreases rewarding effects of alcohol |
marijuana | endocannabinoid R agonist |
ketamine | NMDA R antagonist , dissociative analgesic |
phenycyclidine (PCP) | NMDA R antagonist , dissociative analgesic |
MDMA (ecstasy) | complex effects on monoamines |
methylxanthines (caffeine, theophylline, theobromine) | phosphodiesterase inhibition and adenosine R antagonism |
nicotine | nicotinic cholinergic R agonist |
cocaine | CNS blockade of monoamine transport, esp DA & NE, prolonging catecholamine effects; peripheral Na channel inhibition |
amphetamine | indirect agonist enhancing catecholamine release |
methylphenidate | amphetamine, decreases DA reuptake by inhibiting DAT |
dextroamphetamine | indirect agonist enhancing catecholamine release |
varenicline | partial nicotinic cholinergic R agonist |