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T3 -t4

physiology

QuestionAnswer
• Thyroid Gland is the The largest endocrine gland
• The thyroid gland is compose of composed of colloid filled follicles
• Colloid = thyroglobulin + iodine fills the lumen of the follicles and is the precursor of thyroid hormone
• Thyroid hormones end up attached to thyroid binding globulins (TBG) produced by the liver , some are attached albumin
• Other endocrine cells, the parafollicular cells
• Parafollicular cells produces produce the hormone calcitonin
Synthesis of Thyroid Hormone
Thyroid Hormones Involves two closely related iodine-containing compounds
The two closely related iodine containing compounds of thyroid Both are non-steroid hormones
Name the two non-steriod hormone 1Triiodothyronine (T3)2 Thyroxine (T4)
T4 and T3 bind to thyroxine-binding globulins (TBGs)
Triiodothyronine (T3) is made of what has two tyrosines with three bound iodine atoms
Thyroxine (T4) has has how many molecules two tyrosine molecules plus four bound iodine atoms
What will Triiodothyronine(T3) and Throxine bind to Will Both bind to target receptors,
Triiodothronine(T3) is active how much more thant thyroxine(T4) ten times more active than T4
Throid Hormones Mechanisms of activity is comparable to are similar to steroids
Thyroid Hormones regulates Regulates metabolism
•Thyroid Hormones regulate metabolism by Promoting glycolysis, gluconeogenesis, glucose uptake
•Thyroid hormone regulates metabolism thru Glucose oxidation
•Thyroid Hormones regulates metabolism by Increasing metabolic rate
•Thyroid Hormones regulates metabolism by Heat production
Created by: d1975f
 

 



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