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MOD 4 Ch. 11 quizz
Pharmacy technician chapter 11 quiz
| Question | Answer |
|---|---|
| The study of the hereditary basis of individual differences is called | Pharmacogenetics |
| __________ Is when one drug blocks the activity of metabolic enzymes in the liver | Inhibition |
| MAO inhibitors interact with some foods to result in | Severe hypertension and intracranial hemorrhage |
| If one drug interferes with the elimination of another, the effects of the other drug will be decreased | False |
| Acetaminophen can produce hepatotoxicity | True |
| _______ is when one drug is moved from protein binding sites by a second drug, result in increased effects of the displaced drug | Displacement |
| Lower cardiac output in the elderly tends to slow the distribution of drugs | True |
| _______ is when a patient gets unpleasant physical withdrawal symptoms when a dose of a drug is discontinued or reduced | physiological dependence |
| Human variability is not a significant factor in disposition | False |
| ________ toxic to the liver | Hepatotoxicity |
| _________ is when two drugs with similar pharmacological actions are taken and the effect is equal to that of each drug taken alone | Additive effects |
| APAP is the abbreviation for aspirin, when is a hepatotoxic drug | False |
| ___________ is a chronic and potentially fatal liver disease causing loss of function and resistance to blood flow through the liver | cirrhosis |
| ___________ is a virally caused systemic infection that causes inflammation of the liver | acute viral hepatitis |
| The liver is responsible for the production of albumin in liver failure the production of albumin can be reduced this will have_ on the pharmacodynamics of many drugs | significant effect |
| ___________ is a drug that antagonized the toxic effect of another drug | antidote |
| ________ is a condition in which the thyroid secretions are above normal | Hyperthyroidism |
| Some anticancer drugs are considered carcinogenic | True |
| Warfarin is derived from clover and affects vitamin dependent clotting factors. It is highly protein bound and can be affected by other drugs and changes in diet. IF a patient is prescribed a drug that displaces the warfarin’s attachment to protein the bl | be longer |
| Drugs such as ibuprofen can cause renal failure | True |
| A condition in which thyroid hormone secretion is below normal is | hypothyroidism |
| _____is when two drugs with different sites or mechanisms of action produce greater effects when taken together than when taken alone. | Synergism |
| Which of the following drugs is considered teratogenic | Thalomid |
| An unexpected reaction the first time a drug is taken, generally due to genetic cause | idiosyncrasy |
| Liver disease | hepatic disease |
| Adverse drug reaction that occur with usual doses of drugs | side effects |
| Ability of a substance to cause cancer | carcinogenicity |
| Toxicity of the liver | hepatotoxicity |
| An abnormal sensitivity generally resulting in an allergic reaction | hypersensitivity |
| A chronic and potentially fatal liver disease causing loss of function and resistance to blood flow through the liver. | cirrhosis |
| Ability of a substance to cause abnormal fetal development when given to pregnant women | teratogenicity |
| The ability of a substance to harm the kidneys | nephrotoxicity |
| A potentially fatal hypersensitivity reaction producing severe respiratory distress and cardiovascular collapse | anaphylactic shock |
| Produce a moisture of therapeutic and adverse effects | adverse drug reaction |
| When elements of ingested nutrients interact with a drug and this affects the disposition of the drug | drug-diet interaction |
| When one drug blocks the activity of metabolic enzymes in the liver | inhibition |
| Occurs when one drug with no inherent activity of its own increases the activity of another drug that produces an effect | potentiation |
| A drug that antagonizes the toxic effect of another drug. | antidote |
| When two drugs with different sites or mechanisms of action produce greater effects when taken together than when taken alone. | synergism |
| When one drug is moved from protein binding sites by a second drug. | displacement |
| When a drug causes more metabolic enzymes in the liver to be produces, thus increasing the metabolic activity. | induction |
| When two different molecules associate or attach to each other. | complexation |
| When two drugs with the similar pharmacological actions are taken and the effect is equal to that of each drug taken alone. | additive effects |