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Endocrine 3
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| Generic | Brand | Category | Indications | Side Effects | US Box Warning | Other Notes |
|---|---|---|---|---|---|---|
| testosterone gel (topical) (CS-III) | AndroGel, Fortesta, Vogeixo | Androgen | Male hypogonadism | contact dermatitis, acne, increased prostate specific antigen (PSA), emotional lability, hypertension | secondary exposure may result in virilization (especially in children) | CI in males with breast or prostate cancer and pregnant women, apply in the morning |
| alendronate (PO) | Fosamax | Bisphosphonate | Osteoporosis | dyspepsia, gastroesophageal reflux disease, hypocalcemia, atypical fractures, osteonecrosis of the jaw | CI in patients with hypocalcemia or abnormalitiesof the esophagus; administer ≥30 minutes before food or drink (except plain water); remain upright for 30 minutes following dose to reduce esophageal irritation | |
| cholecalciferol (vitamin D3) (PO) (OTC) | --- | Vitamin D analog | Dietary supplement, osteoporosis prevention | vitamin D toxicity (nausea, vomiting, loss of appetite, constipation, confusion, weakness) | CI with hypercalcemia | |
| sildenafil (PO) | Viagra, Revatio | Phosphodiesterase-5 enzyme (PDE5) inhibitor | ED, PAH | priapism, headache, flushing, visual disturbance, dyspepsia, back pain (mostly with tadalafil), hearing or vision loss (rare) | CI with concomitant use of nitrates (may cause severe hypotension) | |
| tadalafil (PO) | Cialis, Adcirca | Phosphodiesterase-5 enzyme (PDE5) inhibitor | ED, BPH, PAH | priapism, headache, flushing, visual disturbance, dyspepsia, back pain (mostly with tadalafil), hearing or vision loss (rare) | CI with concomitant use of nitrates (may cause severe hypotension) | |
| levothyroxine (PO, IV) | Synthroid, Levoxyl, Unithroid | Thyroid product | Hypothyroidism | weight loss, palpitations, diarrhea, insomnia, heat intolerance | not intended for use for weight loss | narrow therapeutic index drug (therapeutic monitoring is recommended); not all generic products are therapeutically equivalent |
| thyroid, desiccated (PO) | Armour Thyroid | Thyroid product | Hypothyroidism | weight loss, palpitations, diarrhea, insomnia, heat intolerance | not intended for use for weight loss | narrow therapeutic index drug (therapeutic monitoring is recommended); not all generic products are therapeutically equivalent |
| phentermine (PO) (CS-IV) | Adipex-P | CNS stimulant, anorexiant | Short term weight management | tachycardia, hypertension, nausea, dizziness, xerostomia, agitation | only approved for short-term use up to 12 weeks; CI in those with a history of cardiovascular disease or drug abuse, pregnancy, hyperthyroidism, or within 14 days of MAOI therapy |