Most commonly used opioid in dentistry

Tylenol #3, provides greater pain relief

Abusers exhibit dilated pupils (mydariasis)

First natural opiate used for acute of severe pain

is an opioid antagonist and used to treat opioid overdoes

refers to a substance that binds to and activates a receptor in the body

also known as mixed agonist-antagonist opioids, refer to a class of opioids that have both agonistic(activating) and antagonistic(blocking) effects on opioid receptors in the nervous system

are substances that bind to receptors in the body but do not activate them, instead, they block or inhibit the action of agonists

Original name for opioid drugs. Derived from the Greek work, which means "inducing stupor or sleep"

A constellation of psysiologic changes undergone by people who have become physically dependent on a drug or chemical who are abruptly deprived of that substance.

Addiction is a chronic, relapsing brain disease that is characterized by compulsive drug-seeking use despite complications or negative consequences

Substance use disorders

occur when the recurrent use of alcohol and/or drugs causes clinically and functionally significant impairment

the behavior of family or friends who associate with the addict that results in continued substance use disorder

Physiologic tolerance to or psychological dependence on a drug

use of a drug for a disease state in a way considered inappropriate

Physical/physiologic dependence

the state in which the drug is necessary for the continued functioning of certain body process.

Psychologic dependence：

The state in which, following withdrawal of the drug, there are manifestations of emotional abnormalities and drug-seeking behavior

Relapse is the return to drug use after an attempt to stop

with repeated dosing, the dose of a drug must be increased to obtain the same effect

The constellation of symptoms, as specified in the DSM-5, that occurs when a physically dependent person stops taking the drug.

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Pharm week 5

Question	Answer
Codeine	Most commonly used opioid in dentistry
Codeine+tylenol	Tylenol #3, provides greater pain relief
Cocaine	Abusers exhibit dilated pupils (mydariasis)
Morphine	First natural opiate used for acute of severe pain
oxycodone	semi-synthetic opioid
Oxycodone + acetaminophen	percocet
Oxycodone + aspirin	percodan
Naloxone (Narcan)	is an opioid antagonist and used to treat opioid overdoes
Agonist	refers to a substance that binds to and activates a receptor in the body
Mixed opioids	also known as mixed agonist-antagonist opioids, refer to a class of opioids that have both agonistic(activating) and antagonistic(blocking) effects on opioid receptors in the nervous system
Antagonists	are substances that bind to receptors in the body but do not activate them, instead, they block or inhibit the action of agonists
Narcotics	Original name for opioid drugs. Derived from the Greek work, which means "inducing stupor or sleep"
Abstience syndrome	A constellation of psysiologic changes undergone by people who have become physically dependent on a drug or chemical who are abruptly deprived of that substance.
Addiction	Addiction is a chronic, relapsing brain disease that is characterized by compulsive drug-seeking use despite complications or negative consequences
Substance use disorders	occur when the recurrent use of alcohol and/or drugs causes clinically and functionally significant impairment
Enabling	the behavior of family or friends who associate with the addict that results in continued substance use disorder
Habituation	Physiologic tolerance to or psychological dependence on a drug
Misuse	use of a drug for a disease state in a way considered inappropriate
Physical/physiologic dependence	the state in which the drug is necessary for the continued functioning of certain body process.
Psychologic dependence：	The state in which, following withdrawal of the drug, there are manifestations of emotional abnormalities and drug-seeking behavior
Relapse	Relapse is the return to drug use after an attempt to stop
Tolenrance	with repeated dosing, the dose of a drug must be increased to obtain the same effect
Withdrawal:	The constellation of symptoms, as specified in the DSM-5, that occurs when a physically dependent person stops taking the drug.

Created by: YizhouYao

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