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pharma 5

chapter 5 nonopioid analgesics

TermDefinition
Perception the physical components of pain
Reaction the psychologic component of pain
antipyretic the ability to reduce a fever- affecting the hypothalamus (controls body temperature)
Antiinflammatory ability to reduce inflammation
Uricosuric ability to increase the excretion of uric acid in urine
antiplatelet the ability to inhibit the aggregation of platelets in the blood
analgesic ability to reduce or relieve pain
COX Cyclooxygenase- a group of enzymes that convert arachidonic acid into prostaglandins (PGE)
PGE Prostaglandins are chemical mediators that cause inflammation and sensitizes pain receptors, leading to pain
TNF -alpha a cytokine released by cells during the inflammatory response in periodontal disease
aspirin (Bayer, Bufferin) Salicylate. analgesic, anti-inflammatory, antiplatelet, antipyretic prescribed for pain/fever/inflammation/but also myocardial infarction
acetaminophen (Tylenol) p-aminophenol, analgesic, antipyretic
ibuprofen (Advil) NSAID, analgesic, antipyretic, antiinflammatory
naproxen (Aleve) NSAID, longer half-life, analgesic, antipyretic, antiinflammatory
diclofenac (Cataflam) NSAID, analgesic, antipyretic, antiinflammatory, anti-rheumatic (topical)
meloxicam (Mobic) NSAID, analgesic, antipyretic, antiinflammatory, anti-rheumatic
celecoxib (Celebrex) NSAID, analgesic, antipyretic, antiinflammatory, anti-rheumatic
colchicine (Colcrys, Mitigare) Antigout agent. prescribed for acute gout attacks
allopurinol (Zyloprim) antigout agent, prescribed for gout prevention
methotrexate (Otrexup) DMARD, antimetabolite. High doses treat cancer, low doses treat arthritis, or as last resort for canker sores
adalimumab (Humira) DMARD, tnf-alpha inhibitor- treats arthritis
etanercept (Enbrel) DMARD, tnf-alpha inhibitor, treats arthritis
Hydroxychloroquine (Plaquenil) DMARD, antimalarial, can also treat arthritis
Created by: user-2062617
 

 



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