Cardizem, Cardizem CD, Cardizem LA, Cartia XT

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Cardio 2 Drugs 1

Generic	Brand	Indication	Class	Adult Dose	Black Box
amiodarone	Pacerone, Nexterone	Atrial fibrillation	Antiarrythmic Agent, Class III	100 - 200 mg PO once daily	Life-threatening arrythmias (tablet) Pulmonary toxicity (tablet) Hepatotoxicity (tablet) Worsened arrhythmia (tablet)
amlodipine	Norvasc	Hypertension	CCB, Dihydropyridine	2.5 - 10 mg PO once daily	None
amlodipine + benazepril	Lotrel	Hypertension	CCB, Dihydropyridine + ACE inhibitor	Amlodipine 2.5 - 10 mg/ Benazepril 10 - 40 mg PO once daily	Fetal toxicity
apixiban	Eliquis	Atrial fibrillation (stroke prevention), Venous Thromboembolism (VTE) prophylaxis and treatment	Anticoagulant, Factor Xa inhibitor	A Fib: 5 mg PO BID VTE treatment: 10 mg PO BID for 7 days followed by 5 mg PO BID VTE prophyalxis: 2.5 mg PO BID	Spinal/Epidural hematomas; Premature discontinuation increases the risk of thrombotic events
aspirin	None	Antiplatelet	Antiplatelet agent Nonsteroidal Anti-Inflammatory Drugs (NSAID) Salicylate	81 mg PO once daily	None
antenolol	Tenormin	Hypertension	Beta-blocker, Beta-1 Selective	50 - 100 mg PO per day	Cessation of Therapy (abrupt discontinuation can worsen cardiac conditions)
benazepril	Lotensin	Hypertension	ACE inhibitor	10 - 40 mg PO per day	Fetal toxicity
bumetanide	Bumex	Edema or volume overload	Loop diuretic	0.5 -2 mg PO/IV per day	Fluid/electrolyte loss
carvedilol	Coreg, Coreg CR	Hypertension, Heart failure with reduced ejection fraction	Beta-blocker with alpha blocking activity	IR: 3.125 - 25 mg PO BID ER: 20 - 80 mg PO once daily	None
clopidogrel	Plavix	Acute coronary syndrome Ischemic stroke	Antiplatelet, P2Y12 Inhibitor	75 mg PO per day	Diminished antiplatelet effect in patients with two loss-of-function alleles of the CYP2C19 gene
dabigatran	Pradaxa	Atrial fibrillation (stroke prevention), Venous Thromboembolism (VTE) prophylaxis and treatment	Anticoagulant, Direct thrombin inhibitor	A Fib: 150 mg PO BID VTE treatment: 150 mg PO BID	Thrombotic events, Spinal/Epidural hematoma
digoxin	Lanoxin	Atrial fibrillation Heart failure with reduced ejection fraction	Antiarrhythmic agent, Cardiac Glycoside	0.0625 - 0.25 mg PO per day	None
diltiazem	Cardizem, Cardizem CD, Cardizem LA, Cartia XT	Atrial fibrillation	CCB, Nondihydropyridine Antiarrhythmic Agent, Class IV	IR: 120 - 480 mg per day in 3-4 divided doses ER: 120 - 480 mg PO per day in 1-2 divided doses	None
enalapril	Vasotec	Hypertension	ACE inhibitor	5 - 40 mg PO per day	Fetal toxicity
enoxaparin	Lovenox	Venous Thromboembolism (VTE) prophylaxis and treatment	Anticoagulant, Low Molecular Weight Heparin	VTE Prophylaxis: 40 mg subcutaneously once daily VTE Treatment: 1 mg/kg subcutaneously Q12H	Spinal/Epidural hematoma
furosemide	Lasix	Edema or volume overload	Loop diuretic	20 - 80 mg PO per day	Fluid/electrolyte loss
heparin	None	Atrial fibrillation (stroke prevention), Venous Thromboembolism (VTE) prophylaxis and treatment	Anticoagulant	VTE Prophylaxis: 5000 units subcutaneously Q8-12H VTE Treatment: 80 units/kg bolus followed by a continuous infusion of 18 units/kg/hour	None
labetalol	Normodyne, Trandate	Hypertension	Beta-blocker with alpha-blocking activity	100 - 600 mg PO BID	None
lisinopril	Zestril	Hypertension	ACE inhibitor	5 - 40 mg PO per day	Fetal toxicity
lisinopril + hydrochlorothiazide	Zestoretic	Hypertension	ACE inhibitor + Thiazide diuretic	Lisinopril 10-20 mg/Hydrochlorothiazide 12.5 - 25 mg PO per day	Fetal toxicity
metoprolol succinate	Toprol-XL	Hypertension, Heart failure with reduced ejection fraction	Beta-blocker, Beta-1 Selective	12.5 - 200 mg PO per day	None
metoprolol tartrate	Lopressor	Hypertension	Beta-blocker, Beta-1 Selective	25 - 200 mg PO BID	None
nebivolol	Bystolic	Hypertension	Beta-blocker, Beta-1 Selective	5 - 40 mg PO per day	None
potassium chloride	Klor-Con, K-Dur, Micro-K	Hypokalemia	Electrolyte supplement	10 - 80 mEq PO per day in 1-4 divided doses	None
propranolol	Inderal LA, Inderal XL	Hypertension	Beta blocker, non-selective	80 - 160 mg PO per day in 1-4 divided doses (based on IR or ER formulation)	None
ramipril	Altace	Hypertension	ACE inhibitor	2.5 - 20 mg PO per day in 1-2 divided doses	Fetal toxicity
rivaroxaban	Xarelto	Atrial fibrillation (stroke prevention), Venous Thromboembolism (VTE) prophylaxis and treatment	Anticoagulant, Factor Xa inhibitor	A Fib: 20 mg PO per day VTE treatment: 15 mg PO BID for 21 days followed by 20 mg PO per day VTE prophylaxis: 10 mg PO once	Spinal/Epidural hematomas; Premature discontinuation increases the risk of thrombotic events
ticagrelor	Brilinta	Acute coronary syndrome	Antiplatelet, P2Y12 Inhibitor	90 mg PO BID	Bleeding Risk; Diminshed antiplatelet effect when given in combination with aspirin doses > 100 mg daily
torsemide	Demadex	Edema or volume overload	Loop diuretic	5 - 50 mg PO per day	None
verapamil	Calan SR, Verelan, Verelan PM	Atrial fibrillation	CCB, Nondihydropyridine Antiarrhythmic Agent, Class IV	IR: 120 - 480 mg PO per day in 3-4 divided doses ER: 120 - 480 mg PO once daily	None
warfarin	Coumadin	Atrial fibrillation (stroke prevention), Venous Thromboembolism (VTE) treatment	Anticoagulant, Vitamin K Antagonist	1-10 mg PO once daily - Individualized dosing	Bleeding Risk

Created by: mcasada

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