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Week 4
| Question | Answer |
|---|---|
| Perception | The physical components of pain |
| Reaction | The psychologic component of pain |
| Antipyretic | Ability to reduce a fever: affect the hypothalamus (controls the body temperature) |
| Antiinflammatory | Ability to reduce inflammation |
| Urisosuric | Ability to increase the excretion of uric acid in the urine |
| Antiplatelet | Ability to inhibit the aggregation (clumping) of platelets in the blood |
| Analgesic | Ability to reduce or relieve pain |
| COX (cyclooxygenase) | Is an enzyme that converts arachidonic acid into prostaglandins (PGE) |
| PGE | Prostaglandins, is a chemical mediator that causes inflammation and sensitizes pain receptors, leading to pain |
| TNF-a | Is a cytokine that is released by cells during the inflammatory response in periodontal disease |
| aspirin (Bayer, Bufferin) | Salicylate, for pain/fever/inflammation/myocardial infarction/medical emergency |
| acetaminophen (Tylenol) | nonsalicylate, for pain/fever |
| ibuprofen (Advil) | NSAIDs, for pain/fever/inflammation |
| naproxen (Aleve) | NSAIDs, for pain/fever/inflammation |
| diclofenac (Cataflam) | NSAIDs, for pain/fever/inflammation |
| meloxicam (Mobic) | NSAIDs, for pain/fever/inflammation/arthritis |
| celecoxib (Celebrex) | NSAIDs, for pain/fever/inflammation/arthritis |
| colchicine (Colcrys, Mitigare) | Antigout agent, for gout (acute attack only) |
| allopurinol (Zyloprim) | Antigout agent, for gout |
| methotrexate (Otrexup) | DMARD/antimetabolite, for arthritis/last resort for canker sores/cancer |
| adalimumab (Humira) | DMARD/TNF-a inhibitor, for arthritis/ulcerative colitis |
| etanercept (Enbrel) | DMARD/TNF-a inhibitor, for arthritis |
| hydroxychloroquine (Plaquenil) | DMARD/antimalarial, for arthritis/malaria |
| celecoxib (Celebrex) | NSAIDs, for arthritis (topical) |