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Chapter 2 Part 1

Genetics- Exam 2- Fall 2026

QuestionAnswer
What is a gene, according to the slide definition? A nucleotide sequence that codes for RNA.
What are the four main RNA types listed? mRNA, tRNA, rRNA, and sRNA.
What role does small RNA (sRNA) play in the slides? It plays a role in gene regulation.
What is a locus? The precise position of a gene on a chromosome.
What is an allele? An alternative form of a gene.
What does haploid mean? A cell or organism with one complete set of chromosomes.
What does diploid mean? A cell or organism with two complete sets of chromosomes.
What are sex chromosomes? Chromosomes that play a role in sex determination.
What are autosomes? All chromosomes other than the sex chromosomes.
What is a karyotype? A representation of a cell's or organism's chromosome complement, usually ordered by size.
What are homologous chromosomes? Chromosomes with the same genetic structure and loci; their alleles may differ.
What three criteria characterize chromosomes in the slides? Size, centromere position, and banding patterns.
What do chromosome banding patterns help do? Distinguish chromosomes through specific, reproducible staining patterns.
What is the p arm of a chromosome? The short arm; p comes from the French petite.
What is the q arm of a chromosome? The long arm of a chromosome.
What are the four centromere-position categories listed? Metacentric, submetacentric, acrocentric, and telocentric.
What is a metacentric chromosome? A chromosome with a centromere near the middle.
What is a submetacentric chromosome? A chromosome with a centromere somewhat off-center.
What is an acrocentric chromosome? A chromosome with a centromere near one end.
What is a telocentric chromosome? A chromosome with a centromere at the end.
Does chromosome number generally indicate organism size or complexity? No. The basic chromosome number varies by species and is generally unrelated to size or biological complexity.
What are two purposes of cell division listed in the slides? Asexual reproduction in some unicellular organisms and the development/maintenance of multicellularity.
What is asexual reproduction? Reproduction in which cell division produces new individuals without sexual reproduction.
How do most prokaryotes divide? By binary fission.
What happens during binary fission? The chromosome replicates into two identical copies, the copies segregate, and each daughter cell receives one copy.
What are somatic cells? Body cells that may be haploid or diploid and reproduce by mitosis.
What are germ cells in the slides? Diploid cells that undergo meiosis to yield haploid gametes.
What are the two main components of the cell cycle listed? Interphase and mitosis.
What occurs during G1? Synthesis of proteins and RNA; the cell prepares for DNA replication.
What occurs during S phase? DNA synthesis and chromosome replication.
What occurs during G2? Synthesis of proteins and RNA as the cell prepares for mitosis.
Which part of interphase varies most in length? G1.
What is the G0 stage? A stage entered when a cell withdraws from the cell cycle, either postponing division or committing never to divide again.
What is the restriction point? The point late in G1 at which a cell commits to initiate DNA synthesis and complete the cycle.
How many chromosomes does a human cell have in G1? 46 distinct chromosomes.
What happens to chromatids during S phase? Chromosomes replicate, so the cell ends S phase with twice as many chromatids as chromosomes present in G1.
What is a sister chromatid? One of the two replicated copies of a chromosome, joined to its sister at the centromeric region.
What is a dyad? A replicated chromosome consisting of a pair of sister chromatids.
What is a monad? A single chromatid as a distinct unit.
Why is the term chromosome relative to cell-cycle stage? In G1 and late M it refers to the equivalent of one chromatid; in G2 and early M it refers to a pair of sister chromatids.
What is mitosis used for? Ordinary growth, repair, and replacement; it is an asexual process.
In which cells does mitosis occur, according to the slides? Somatic cells and during early germline development.
What is the outcome of mitosis in a diploid cell? One division produces two diploid daughter cells.
What is karyokinesis? Division of the nucleus.
What is cytokinesis? Division of the cytoplasm.
What are the five stages of mitosis in order? Prophase, prometaphase, metaphase, anaphase, and telophase.
What happens to chromatin during prophase? It shortens and thickens, forming condensed chromosomes.
What happens to the nuclear envelope and nucleolus in prophase? The nuclear envelope breaks down and the nucleolus/nucleoli disappear.
What happens to centrosomes during prophase? They migrate to opposite cell poles.
What is the mitotic spindle made of? Microtubules.
How are microtubules formed? By rapid polymerization of tubulin proteins.
What do astral microtubules do? Help position the spindle apparatus.
What do polar microtubules do? Help push the spindle poles away from each other.
What do kinetochore microtubules do? Attach to kinetochores bound to chromosome centromeres.
What happens during prometaphase? Spindle microtubules capture sister-chromatid kinetochores; the two kinetochores of a pair attach to microtubules from opposite poles.
What happens if a spindle microtubule does not contact a kinetochore? It depolymerizes and retracts toward the centrosome.
What happens during metaphase? Chromosomes reach maximum contraction and sister-chromatid pairs align at the metaphase plate.
What happens during anaphase? The centromeric region divides and sister chromatids separate, becoming individual chromosomes moving to opposite poles.
What happens to kinetochore microtubules during anaphase? They shorten as chromosomes move toward opposite poles.
What happens to polar microtubules during anaphase? They lengthen, moving the poles farther apart.
How do motor proteins help chromosome movement? They use energy from ATP hydrolysis to aid movement of sister chromatids toward opposite poles.
What happens during telophase? Chromosomes reach the poles, uncoil into diffuse chromatin, nuclear membranes reform, and spindle fibers disappear.
How does cytokinesis occur in animal cells? A cleavage furrow develops.
How does cytokinesis occur in plant cells? A cell plate develops between the daughter cells.
What are coenocytic cells? Cells in which cytokinesis is deferred or absent; the slides note that they are common in fungi.
What is the significance of mitosis for chromosome number? It maintains a constant chromosome number in daughter cells.
How does mitosis support multicellularity? Repeated mitosis and cytokinesis enable growth and development of multicellular organisms.
Created by: KristenR2025
 

 



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