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Chapter 28

Genetics- Exam 2- Fall 2026

QuestionAnswer
What is quantitative genetics? The study of traits that can be described numerically.
What are complex traits? Traits usually controlled by more than one gene and significantly influenced by environmental factors.
Give two examples of complex traits from the slides Height and metabolic rate.
Why is quantitative genetics important to breeders? Many key characteristics considered by plant and animal breeders are quantitative traits.
How can genes influence human disease? Many human diseases are influenced by several genes.
How can quantitative traits aid adaptation? Many traits that allow a species to adapt to its environment are quantitative traits.
What is a quantitative trait? Any trait that varies measurably within a given species.
How may quantitative traits be measured? Numerically, such as weight in kilograms, speed in km/h, or glucose burned per minute.
Can behavioral traits be quantitative? Yes. For example, the duration and pattern of a mating call can be measured.
What is a continuous trait? A trait that varies along a continuum rather than falling into discrete categories.
What is a meristic trait? A trait expressed in whole-number counts, such as the number of bristles on a Drosophila back.
What is a discontinuous trait? A trait that falls into two or more distinct categories.
Give an example of a discontinuous trait from the slides. White or red eyes in fruit flies.
What is continuous variation? A range of phenotypes within a group that cannot naturally be sorted into a small number of discrete categories.
What is a frequency distribution? A way to describe quantitative variation by dividing a trait's range into phenotypic categories and counting individuals in each.
How were student heights categorized in the slide example? The range of heights was partitioned into one-inch intervals.
What is a normal distribution? A symmetrical, bell-shaped distribution in which values vary around an average.
What is the typical shape of many quantitative-trait distributions? Approximately symmetrical and bell-shaped, resembling a normal distribution.
What is polygenic inheritance? Transmission of traits governed by two or more genes.
How do most quantitative traits behave? They are polygenic and exhibit a continuum of phenotypic variation.
What is a quantitative trait locus (QTL)? A chromosomal location or region that affects the outcome of a quantitative trait.
What can a QTL contain? One or more genes.
How are QTLs identified? They are chromosomal regions identified through gene mapping.
What did Kolreuter observe when crossing tall and dwarf tobacco plants? The F1 plants were intermediate in height, and the F2 generation showed a broad distribution of heights.
What did Kolreuter's tobacco experiment suggest? A trait showing continuous variation could be inherited through multiple factors, although he did not understand the significance at the time.
Who demonstrated continuous variation related to polygenic inheritance in wheat in 1909? Herman Nilsson-Ehle.
What wheat trait did Nilsson-Ehle study? Red pigment in the hull of wheat, Triticum aestivum.
What happened when true-breeding red wheat was crossed with true-breeding white wheat? The F1 generation had intermediate-red hulls; the F2 showed wide variation in redness, including white.
What is the multiple-gene or multiple-factor hypothesis? The hypothesis that many genes or factors contribute quantitatively to a phenotype.
According to the hypothesis, how many genes influence the hereditary component? At least two genes contribute to the phenotype in an additive way.
What does additive gene action mean in the slides' model? The contributions of additive alleles at different loci accumulate to influence the phenotype.
What assumption does the model make about additive alleles at each locus? Their effects are equivalent.
What dominance assumption is made by the simple multiple-factor model? No allelic pair exhibits dominance of one allele over the other.
What assumption does the model make about interactions between loci? No gene interactions occur among alleles at different loci in the polygenic series.
What linkage assumption does the model make? The genes in the polygenic series are not genetically linked.
In the wheat hull-color example, what do A and B represent? Two gene loci whose additive alleles contribute to red pigment.
What is the genotype of the true-breeding red parent in the wheat example? AABB.
What is the genotype of the true-breeding white parent in the wheat example? aabb.
What is the F1 genotype from AABB × aabb? AaBb.
Why do F2 wheat hull colors form a range? Different F2 genotypes carry different numbers of additive red alleles.
What F2 phenotypic ratio is shown for the two-gene wheat hull-color example? 1:4:6:4:1, from the most red to the white extreme.
How many additive alleles are present in AABB? Four; this produces the reddest phenotype in the example.
How many additive red alleles are present in aabb? Zero; this produces the white phenotype in the example.
What phenotype is associated with AABB in the slide table? Red
What phenotype is associated with AABB in the slide table? White
What phenotype is associated with AABb or AaBB? Dark pink
What phenotype is associated with AAbb, AaBb, or aaBB? Medium pink
What phenotype is associated with Aabb or aaBb? Light pink
Why is quantitative-trait analysis difficult? Multiple genes control the traits, and environmental factors can substantially affect the phenotype.
How can the environment affect seed weight? Environmental conditions can cause individuals with the same genotype to produce seeds of different weights.
How does one gene with little environmental variation affect genotype–phenotype matching? The three genotypes can fall into distinct, non-overlapping phenotypic categories.
What happens when environmental variation increases for a one-gene trait? Phenotypic ranges of different genotypes can overlap, making genotype harder to infer.
How does having three genes affect overlap between genotypes and phenotypes? It creates more phenotypic classes and can make genotype identification more difficult, especially when environmental effects are substantial.
What is the F2 phenotypic ratio for one gene pair in the heterozygote cross described? 1:2:1.
What F2 phenotypic ratio is given for three gene pairs in the slide example? 1:6:15:20:15:6:1.
How is the proportion of individuals at either extreme in the F2 related to the number of gene pairs? The ratio for either extreme phenotype is 1/4ⁿ, where n is the number of gene pairs involved.
How can the number of gene pairs be estimated from an extreme-phenotype proportion? Use the relationship that the proportion at either extreme is 1/4ⁿ and solve for n.
How many distinct F2 phenotypic classes are predicted by the model? 2n + 1, where n is the number of gene pairs.
What is the expected number of F2 phenotypic classes for two gene pairs? 2(2) + 1 = 5 classes.
What is the expected number of F2 phenotypic classes for three gene pairs? 2(3) + 1 = 7 classes.
What is the main distinction between genotype and phenotype in quantitative genetics? Genotype is the genetic makeup; phenotype is the observable trait, which can also be influenced by the environment.
Created by: KristenR2025
 

 



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