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QuestionAnswer
Amphetamines(Adderall) use increase dopamine and norepinephrine in the brain
Methylphenidate(Ritalin) Increases dopamine and norepinephrine levels in the CNS
Black box warning for stimulants MI, sudden death
What should you report for patients on stimulants? Headache, dizziness, tachycardia, palpitations, or anorexia, tremors
What medications should be avoided? Cold medications, especially decongestants and st johns wort
What schedule are stimulants? Schedule II
What are medication vacations? To prevent physical dependency.
What lab does fluoxetine require? SE? CBC with differential, side effects include serotonin syndrome, seizures, suicidal thoughts, torsades de pointes
What is fluoxetine contraindicated in? Bipolar, cardiac, seizures, current SI, MAOI, warfarin/NSAIDs, st johns wort, digoxin
Memantine use NMDA receptor antagonist, preventing binding of glutamate. Used for alzheimers
SE of Memantine HA, dizzy, N/V/D, anorexia, abdominal pain
Severe sx of memantine Hepatotoxic, nephrotoxic, bradycardic, heart block, confusion
COntraindications to memantine Epilepsy, MI, HF, kidney/liver disease. Can be taken with donepezil.
Memantine interactions Cough meds, warfarin, amantidine, ketamine. Meds increasing urine pH decrease excretion.
Do you have to worry about food timings with memantine? Taken without regard for food.
Donepezil A cholinergic ACHe inhibitor that improves memory
MAOIs can cause what when taken with CNS stimulants? Hypertensive crisis.
Patients on atomexetine should have routine LFTs
What can risperidone cause? Rapid eye blinking, neck spasms, repeated muscle contraction (EPS)
When experiencing EPS, what do you expect the provider to order? Decreased dose or discontinue med
No NSAIDS with donepezil.
What organ do you have to monitor on memantine? BUN/creatinine, GFR, LFT, Hct/hgb. Kidneys.
Serotonin syndrome sx HTN, HA, tremots, agitation.
Created by: pharm3studysets
 

 



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