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immuno exam 3
| Question | Answer |
|---|---|
| what blood group antigens do exhibit dosage | Rh (except for D), Kidd, Duffy, MNSs, lutheran |
| Kell system antigens | K and k |
| most common kell genotype | kk |
| what phase is Kell detected | AHG |
| what kind of immunoglobulin is kell? | IgG |
| can Kell cause HDN and HTR | yes |
| McLeod syndrome is seen with what blood group system | Kell |
| K is associated with | chronic granulomatous disease |
| Kidd antibodies are which immunoglobulin | IgG |
| Duffy blood group antigens | Fya and Fyb |
| Fy(a-b-) in blacks is associated with | resistance to plasmodium vivax |
| Duffy blood group antibdodies are | IgG |
| can duffy cause HDN and HTR | yes |
| duffy response to enzymes | destroyed |
| M and N are located on | glycophorin A |
| S and s are located on | glycophorin B |
| M and N are detected at | IS |
| M and N are | IgM - naturally occuring |
| M and N are considered to be clinically _______________ | insignificant |
| Anti-U is an ____ antibody and can | IgG and can cause severe HTR and HDN |
| P blood group response to enzymes | enhanced |
| lutheran blood group antigens at birth | not very well developed |
| I antibody is associated with | cold agglutinin disease |
| lewis blood group antibodies are | naturally occuring - IgM |
| alloantibodies vs autoantibodies | allo - against foreign materials auto - formed against self |
| check cells | coated with IgG and should react with AHG. work as quality control |
| AHG | antihuman globulin |
| AGT | antiglobulin test |
| which kell phenotype is rarest | KK |
| how is a DAT performed | AHG is added to washed cells, which are then centrifuged and examined |
| cold antibodies are ____ and warm are _____ | IgM; IgG |
| which antigens are destroyed by enzyme treatment | Duffy, Xga, Ss, MN |
| Kidd is associated wtih | delayed HTR |
| cord blood cells are what lewis type | Le(a-b-) |
| which systems are most often associated with HTR | ABO, Rh, Kell, P |
| check cells are | antibody coated, O negative cells |
| hydatid cyst fluid is used to | neutralize P1 substances |
| what group actually gets stronger with enzymes | Rh |
| what antibody doesnt usually react with cord cells | anti-I |
| what genes must be inherited for ABH antigens to appear in secretions? | H and Se |
| cord cells contain | i antigen |
| the saline phase is designed to detect | IgM antibodies and ABO grouping errors |
| majority of HTR is caused by | clerical errors |
| the compound antigen f represents | c and e |
| lewis blood group antibodies are more likely to form in | pregnant women |
| check cells are coated with | IgG |
Created by:
kingsleya27