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TOSCE/OSCE Fall 2026
P2 Fall TOSCE/OSCE Drug List
| Generic | Brand | Category | Indications | Side Effects | US Box Warning | Other Notes |
|---|---|---|---|---|---|---|
| hydralazine (PO, IV) | Apresoline | Direct arterial vasodilator | HTN | hypotension, drug-induced lupus-like syndrome | CI in CAD | |
| fluoxetine (PO) | Prozac | Selective serotonin reuptake inhibitor (SSRI) | MDD | drowsiness, insomnia, nausea, vomiting, xerostomia, sexual dysfunction, headache, diaphoresis | increased risk of suicidal thinking and behavior in children, adolescents, and young adults | CI within 14 days of MAOI |
| methylphenidate (PO, transdermal) (CS-II) | PO: Concerta, Ritalin Patch: Daytrana | CNS stimulant | ADHD, narcolepsy | insomnia, headache, anxiety, weight loss, decreased appetite, hypertension | high potential for abuse | CI within 14 days of MAOI |
| metoprolol succinate (PO) | Toprol-XL | Beta1-selective beta-blocker | HF, AF (rate control), CAD, HTN | bradycardia, hypotension | masks symptoms of hypoglycemia | |
| metoprolol tartrate (PO, IV) | Lopressor | Beta1-selective beta-blocker | AF (rate control), CAD, HTN | bradycardia, hypotension | avoid abrupt discontinuation | masks symptoms of hypoglycemia |
| sulfamethoxazole and trimethoprim (PO, IV) | Bactrim, Bactrim DS | Sulfonamide antibiotic | SSTI, cystitis, pyelonephritis, opportunistic infection prophylaxis Activity against: MRSA, Enterobacteriaceae | nausea, vomiting, diarrhea, skin rashes (rarely SJS or TEN), photosensitivity, crystalluria, hyperkalemia, increased serum creatinine, hypersensitivity reactions | ||
| gabapentin (PO)(CS-V) | Neurontin | Anticonvulsant | Seizure disorders, neuropathic pain | somnolence, dizziness, ataxia, fatigue, diplopia, xerostomia, blurry vision, peripheral edema, weight gain | ||
| clonazepam (PO) (CS-II) | Klonopin | Benzodiazepine | Anxiety, seizure disorders | daytime sedation, performance impairment, tolerance, dependence, anterograde amnesia, withdrawal, dizziness, ataxia | risk o f profound sedation, respiratory depression, coma and death with opioids; risk of abuse, misuse, and addiction; risk of dependence and withdrawal reactions | |
| ibuprofen (PO) | Motrin, Advil | NSAID | OA, RA, acute pain | diarrhea, dyspepsia, abdominal pain, flatulence, nausea | may increase the risk of serious (and potentially fatal) cardiovascular thrombotic events, MI, and stroke; may increase the risk for serious GI adverse events including ulceration, bleeding, and perforation | may reduce renal blood flow and compromise existing renal function (avoid in patients with renal disease, heart failure, and cirrhosis) |
| levothyroxine (PO, IV) | Synthroid, Levoxyl, Unithroid | Thyroid product | Hypothyroidism | weight loss, palpitations, diarrhea, insomnia, heat intolerance | not intended for use for weight loss | narrow therapeutic index drug (therapeutic monitoring is recommended); not all generic products are therapeutically equivalent |
| cefdinir (PO) | Omnicef | Beta-lactam antibiotic (third generation cephalosporin) | Otitis media, bacterial sinusitis Activity against: Streptococcus pneumoniae, Haemophilus influenzae | diarrhea, hypersensitivity reactions | ||
| carbamazepine (PO) | Tegretol | Anticonvulsant | Seizure disorders, bipolar disorder | dizziness, drowsiness, headache, ataxia, nausea, vomiting, hyponatremia | risk of serious dermatologic reactions (including SJS and TEN) in patients with certain genetic predisposition; may cause aplastic anemia and agranulocytosis | |
| rivaroxaban (PO) | Xarelto | Anticoagulant, factor Xa inhibitor | AF (stroke prevention), VTE, PAD | bleeding | premature discontinuation increases risk of thrombotic events; increased risk of epidural or spinal hematoma in patient undergoing spinal puncture | |
| acetaminophen (PO, PR, IV) | PO/PR: Tylenol IV: Ofirmev | Analgesic (non-opioid), antipyretic | Pain, fever | nausea, vomiting, increased hepatic transaminases | total daily dose from all sources should not exceed maximum daily limit; hepatotoxicity | |
| escitalopram (PO) | Lexapro | Selective serotonin reuptake inhibitor (SSRI) | MDD | drowsiness, insomnia, nausea, vomiting, xerostomia, sexual dysfunction, headache, diaphoresis | increased risk of suicidal thinking and behavior in children, adolescents, and young adults | CI within 14 days of MAOI; do not discontinue abruptly |
| atorvastatin (PO) | Lipitor | HMG-CoA reductase inhibitor | Dyslipidemia, CAD, stroke | myopathy/rhabdomyolysis | avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding | |
| lisinopril (PO) | Prinivil, Zestril | Angiotensin-converting enzyme (ACE) inhibitor | HTN, HF, CAD | cough, hyperkalemia, angioedema, hypotension | fetal toxicity (CI in pregnancy) | |
| codeine and acetaminophen (PO) (CS-II) | Tylenol with Codeine #3, Tylenol with Codeine #4 | Opioid and nonopioid analgesic combination | Pain | dizziness, drowsiness, nausea, vomiting, constipation, pruritus, respiratory depression (dose-related) | ||
| metformin (PO) | Fortamet, Glutmetza, Riomet | Biguanide | Type 2 DM, PCOS | diarrhea, nausea, vomiting, Vitamin B12 deficiency | lactic acidosis | CI with eGFR <30 |
| amlodipine (PO) | Norvasc | Dihydropyridine calcium channel blocker (CCB) | HTN, CAD | peripheral edema, hypotension |