click below
click below
Normal Size Small Size show me how
Quiz crash course
| Question | Answer |
|---|---|
| Cyclosporine | immunosuppress, inhibits helper T cells, onset 7-14 days |
| Methotrexate | Antineoplastic, folic acid analog, blocks enzyme that makes folate. Slows prog of RA through adenosine. 1 time per week. |
| Methotrexate is toxic to what systems? | Hepatic and pulmonary toxic. Absorption delayed on food |
| Contraindications to methotrexate | Ulcerative stomatitis, pancytopenia, diarrhea, NSAIDs, infection |
| Entacapone | Antiparkinsons, COTM, prolongs effects of levadopa, can cause brown urine, hypotension |
| Contraindications to entacapone | MAOI, psychosis |
| Benztropine | antiparkinson anticholinergic, blocks acetylcholine decrasing tremors, rigidity, and EPS. |
| Benztropine does NOT relieve | Tardive dyskinesia. May cause heat intolerance and narrow angle glaucoma. |
| Botulinum A | Antispasmodic anticholinergic, inhibits acetylcholine causing temporary paralysis. Used for cervical dystonia, migraines, overactive bladder, parkinsons. |
| Adverse effects to botulinum A | Ptosis, anaphylaxis, death |
| Levadopa | Dopamine, while carbidopa prevents breakdown. Can cause darkened excretions, confusion, depression, anemias, intraocular pressure. |
| Cyclobenzaprine | Central muscle relaxant. Catecholamine reuptake inhibitor. Acts in brain stem short term med for acute spasms, does not work on CNS disorders, may cause angioedema. |
| Cyclobenzaprine can cause | hyperpyretic crisis and seizures |
| Carbamazepine | Antiseizure medication, mood stabilizer, inhibits voltage gated sodium, used for severe prevention. Take with food at night to relieve daytime sedation. Do not take MAOIs for 2 weeks. |
| Baclofen | Antispasmodic, activates GABA B, used for SCI, MS, CP, do not stop abruptly. |
| Dantrolene | Skeletal relaxant, antispasmodic, blocks reuse of calcium from storage sites can cause CV and vent fib with verapamil and diltiazim. |
| Rifampin | Inhibit bacterial RNA synthesis, hepatotoxic, orange excretions |
| Isoniazid | Antitubercular, hepatotoxic, optic neuritis, blurred vision |
| Pyrixidone | Treats inh associated neuropathy, take on empty stomach 1 hour before or 2 hour after. avoid tyramine and histamine. |