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Dantrolene Sodium

QuestionAnswer
Dantrolene T/P T: Skeletal Muscle relaxant P: Direct acting antispasmodic, calcium release blocker
Dantrolene MOA Blocks release of calcium from storage sites within skeletal uscle directly decreasing skeletal muscle contractions and spasms.
Dantrolene uses Decrease spasticity associated with SCI, CP, MS
Adverse effects of Dantrolene Muscle weakness, drowsiness, hepatotoxicity, liver failure, can cause serious hepatitis and fatal liver failure
What drugs can cause ventricular fib and CV when combined with Dantrolene Verapamil/diltiazem
What should be avoided while on dantrolene? Avoid alcohol, use cautiously with other CNS depressants.
Created by: pharm3studysets
 

 



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