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Baclofen

QuestionAnswer
Baclofen T/P T: centrally acting antispasmodic P: Skeletal muscle relaxant
Baclofen MOA Activates GABA- B receptors, decreasing excitatory neurotransmission in the spinal cord, and reducing muscle spasticity.
What is baclofen used for? Used for SCI, MS, CP
Adverse effects of baclofen drowsiness, cns depression, dizziness, fatigue
Important education Do not stop abruptly, can cause rebound spasticity, AMS, seizures
What should be considered before administration? Consider renal function, additive, CNS depression, with other meds. Use caution withdrawing or activities requiring alertness.
Created by: pharm3studysets
 

 



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