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Carbamazepine
| Question | Answer |
|---|---|
| Carbamazepine T/P | Antiseizure, antiepileptic; mood stabilizer |
| Carbamazepine MOA | Decreases synaptic transmission in the CNS by inhibiting voltage gated sodium channels in neurons |
| Carbamazepine Uses | Prevention of seizures, tx of mania, relief of pain in trigeminal neuralgia |
| Carbamazepine side effects | dizziness, drowsiness, ataxia, headache, blurred vision, leukopenia, anemia, thrombocytopenia |
| Carbamazepine serious side effects | SJS, BMS, suicidal ideation, mild anticholinergic effects. |
| Interactions with Carbamazepine | phenytoin, warfarin, oral contraceptives, grapefruit juice |
| Contraindications to Carbamazepine | Hypersensitivt yto drug or tricyclic antidepressants. MAOI use within the last 14 days. |
| Lab tests to monitor with Carbamazepine | CBC, LFT, iron, thyroid |
| When should Carbamazepine be taken? | Take with food and at night to reduce daytime sedation. |
| Females should use non-hormonal contraceptives |