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Bio 110 - Unit 2

What's a cell, Cells do

QuestionAnswer
Cell theory 1) all organisms are made of one or more cells 2) cells come from existing cells
What is a cell Functions to separate the initial aqueous regulated cell from the external unregulated environment - think homeostasis
Phospholipid bilayer hydrophilic head and hydrophobic tail - embedded into the membrane allow movement across by ions (charged particles), sugars, necessary large and charged molecules
Cell membrane (prokaryotes and eukaryotes) semi-permeable - selectively permeable to control the internal environment Can pass: small, uncharged molecules cannot pass: large and charged molecules - controls what moves in and out of the cell
Proteins embedded into the membrane, allow movement across by ions (charged particles), sugars... necessary large and charged particles
carbohydrates surface perceive pathogens and other molecules
passive transport - no energy - diffusion - movement of solutes - osmosis - movement of water - facilitated diffusion - charged and/or large molecules
active transport - requires energy - requires a protein - against gradient
sodium potassium pump example for protein pumps into cell membrane and active transport - cell membrane, helps healthy cell function, against concentration gradient
solute substance that is being dissolved
solvent what the solute is being dissolved into
solution combination of solute and solvent
diffusion - movement of molecules from high solute -> low solute conc. - moves with concentration gradient, not against it - equilibrium is reached when there is an equal distribution of solute molecules
Osmosis - movement of water across semi-permeable membrane - water moved from high (water) -> low (water) concentration - solutes stay behind
hypertonic more solute than solvent
hypotonic more solvent than solute
isotonic balance of solute and solvent
plasmolysis when water moves from the inside to the outside of the cell
hemolysis excess water going into red blood cell causing it to burst
endocytosis - for substances too big for passive or active transport - cells engulf them with their plasma membrane
exocytosis - removes large subs from the cell - both use vesicles: a pocket-like structure surrounding a substance so that it can be moved in or out of the cell
domains and life domains are the largest category used by scientists to organize life - three domains that incorporate all life - bacteria: beneficial, harmful, or neutral to critters - archaea: extremophiles - ex: hydrothermal vents - eukarya: eukaryotic (organelles)
Bacteria - oldest - prokaryotic - single-celled organisms - broader diversity of modes of nutrition and reproduction than Eukarya
Archaea - middle - prokaryotic - more closely related to eukaryotes - thrive in extreme environments - understudied (hard to reach)
Eukarya - youngest - eukaryotic - includes humans and all living organisms that can be seen by the naked eye ex) protista, fungi, plantae, animalia
All Cells Plasma membrane, Cytoplasm, and genetic material (DNA and/or RNA), ribosomes
Eukaryote Cells has a nucleus (contains genetic material) and organelles (think small organs that specialize in a specific function), single or multicellular - animals, plants, fungi, and protists
Prokaryote cells don't have a true nucleus (more of a nuclear region), no organelles, first cells on earth, high metabolic diversity, single celled - bacteria and archaea
Eukaryotic cell - Plant cells - cell wall - cell membrane - cytosol/cytoplasm - chloroplasts - central vacuole
cell wall (plants) - made up of cellulose and gives cells its shape - minimizing water loss - structure and protection
cell membrane - eukaryotic plant cell - up against cell wall
cytosol/cytoplasm (eukaryotic and prokaryotic) watery matrix that keeps organelles suspended - get matrix to fill the cell
chloroplast (plant and algae) - where photosynthesis occurs - small green spheres - chlorophyll pigment - originally a bacteria that was taken in by a eukaryote by endosymbiosis - makes sugar
central vacuole (plant and animal) - organelle filled with water and solutes - nutrition and waste - in other eukaryotes, but less prominent - storage
eukaryotic cells - animal cells - cell membrane - nucleus - cytosol/cytoplasm - mitochondria - lysosomes - rough endoplasmic reticulum - smooth endoplasmic reticulum - golgi apparatus
cell membrane - eukaryotic animal cell - fluid - permits permeability - does not have cell wall
nucleus - eukaryotic animal cell - stores the cells hereditary information or DNA - coordinates the cells activities
cytoskeleton - acts as the inner scaffolding for the cell - provides shape and support - enables movement - internal structure
microtubules - thick, hollow tubes - the tracks to which molecules and organelles within the cell may attach and be moved along
intermediate filaments - durable, rope-like systems of numerous overlapping proteins - give cells great strength
microfilaments - long, solid rope-like fibers - help with cell contraction and cell division
eukaryotic cells - animal cells structure cytoskeleton - three types of protein fibers in cytoskeleton - microtubules - intermediate filaments - microfilaments
mitochondria (plants and animals) - in most eukaryotes - energy source (powerhouse of the cell) -> makes ATP - breaking chemical bonds from carbohydrates, fats, proteins - originally a free-living bacteria, endosymbiosis
lysosomes (animals) - waste removers - contains ~ 50 different digestive enzymes - breaks down waste
rough endoplasmic reticulum (plant and animal) - rough ER - makes proteins (makers and doers) - has ribosomes
smooth endoplasmic reticulum (plant and animal) - smooth ER - makes lipids and carbohydrates
Golgi apparatus (plant and animal) - processes molecules - packages and sends
specialized cell cell structure is different to match it's function
cell specialization theme - for an organism to function properly cells need to specialize to cover different requirements within the body - to maintain homeostasis many different tasks are needed -> different cell types
specialized cells human examples: - Red blood cells - have hemoglobin to carry oxygen, round shaped, don't have nucleus to carry more oxygen - White blood cells - two types - Muscle cells - smooth, skeletal, and cardiac - Neurons - send and receive electrical signals (thoughts/senses)
nucleus (plant and animal) holds DNA and organizes cell
ribosomes (prokaryotes and eukaryotes) - makes proteins
Types of life on earth Autotrophs and Heterotrophs
Autotrophs - inorganic substances (CO2) turned into food - Plants, algae, some bacteria
photoautotrophs use light to fuel process - plants, green algae,
heterotrophs - rely on other organisms as their source of nourishment - animals (humans), fungi, some bacteria
Photosynthesis - uses light energy to convert CO2 and H2O into glucose - end products glucose and oxygen are vital for almost all life - takes place in the chloroplasts through it's photopigments
photopigments capture energy from sunlight - most common is chlorophyll a (Blue-green)
Photosynthesis occurs in chloroplasts - between the thylakoids - light energy becomes chemical energy - thylakoid is a single portion of stroma
Light spectrum and photopigments white light composed of 6 types of color - violet, blue, green, yellow, orange when light strikes object: absorbed, transmitted, reflected
Absorbed light - wavelengths that do NOT make up the color of the object - energy transferred to object - provides light energy for photosynthesis - chlorophyll does not absorb all wavelengths equally
reflected light color of the object
chlorophyll a - most important light-absorbing pigment in plants - does not absorb light in the green part of the spectrum
accessory pigments aid chlorophyll a in photosynthesis by absorbing light of different wavelengths
first half of photosynthesis focuses on obtaining energy
second half of photosynthesis focuses on storing energy
Photosynthesis equation 6 Carbon dioxide + 6 water -> glucose + 6 oxygen
cellular respiration equation glucose + 6 oxygen -> 6 carbon dioxide + 6 water + ATP
Cellular respiration - glucose is a carb (store energy in their chemical bonds) - aerobic (oxygen present) pathways that break down glucose - extracts energy stored in chemical bonds - goal is to produce ATP (energy currency of cell)
Cellular respiration and enzymes biochemical pathway medicated by enzymes - (mostly) proteins specialized to catalyze a chemical reaction - speeds up reaction - bind substrate (molecule) at active site - enzyme substrate specificity - enzyme can be reused
ATP Synthase enzyme that synthesizes ATP from ADP - final stage of cellular respiration where ATP is produced
Glycolysis breaks glucose into 2 pyruvate molecules - produces 2 ATP - Occurs in the cytoplasm of a cell
Pyruvate to acetyl CoA - Pyruvate breaks apart into acetyl CoA, with carbon dioxide as a byproduct - No ATP is produced - Occurs in the cytoplasm of cell
Krebs cycle also known as citric acid cycle - occurs in the mitochondria (matrix) - carbon dioxide byproduct - produces 2 ATP
Oxidative Phosphorylation - electron transport chain - electron shuffle (move electrons across membrane back and forth to make atp) - Majority of ATP is made here (32) - occurs in the inner membrane of the mitochondria - final byproduct is water - final electron acceptor is oxygen
Fermentation Plants, animals, and many other critters perform Aerobic respiration (with oxygen) - Fermentation is anerobic respiration (no oxygen) who: bacteria, archaea - Just glycolysis (doesn't need oxygen) - yeast, muscle cells
fermentation process makes less ATP than aerobic respiration - glycolysis - glucose -> pyruvate costs ATP to start produces 2 ATP and 2 NADH
Cell division cells will have different functions to support the homeostasis of the organism - multicellular organisms grow by creating more cells via cell division
uncontrolled cell division - cancer - unable to communicate - unable to perform normal cell functions - unanchored -> travel
cancer possible causes - toxins - genetics - radiation
Uncontrolled growth leads to tumor growth
Cancer possible treatment - radiation - medication many treatments target rapidly dividing cells (often cancer) -> hair also being affected
Cell cycle checkpoints - cell cycle had built in checkpoints to prevent harmful mutations and cancer - issue with the cell -> apoptosis (cell self-destruction) - fixable issue -> pause to correct error
G0 Phase cells that are performing their function but not preparing for replication
cell cycle - most of the time a cell is in interphase - metaphase is very brief
G1 and G2 - growth phases to prepare and check the cell for division G1: Cytoplasm and cellular structures
synthesis phase - replicates chromatin (DNA replication) - ends with 2 sister chromatid connected to a centromere
G2 centrioles duplicate
M phase mitosis or meiosis
Somatic cells body cells, diploid, mitosis
mitosis cellular division that results in two identical daughter cells
germ cells gametes, haploid, meiosis
meiosis cellular division that results in four individual gametes (sex cells) containing HALF of the parent cells genetic material
Receptors receive signal molecules on the outside (or inside of the cell) cell signals are ligands - ligands can be diverse type of molecules
transduction receptors change shape and pass message on; amplifying message
intercellular cell to cell communication
intracellular inside the cell
examples - intercellular signaling - direct contact - paracrine signaling (targeted message) - synaptic signaling in the brain - endocrine signaling (hormones)
Purpose of cellular division (mitosis) growth and repair - different cells have different jobs (homeostasis) - only a small part of the cell cycle
nucleus holds DNA -> DNA replicates exactly... - chromosomes - DNA and Protein (to help with organization) - humans have 46 chromosomes - all chromosomes duplicated in interphase
sister chromatids are held together by centromeres
PMAT + Cytokinesis - Prophasse - metaphase - Anaphase - telaphase - cytokinesis - cell membrane contracts to split into 2 cells
Prophase centrioles migrate and form spindle fibers
metaphase spindle fibers attach to centromere, equatorial plate
anaphase spindle fibers pull
telephase cytokinesis 1) cleavage furrow 2) cell plate: center outward
Binary fission - prokaryotes - circular chromosomes: replicate by pairing inside the chromosome - enlarge similar to interphase and separate similar to cytokinesis - mother and daughter cells are identical
Created by: Shannonneville
 

 



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