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TOSCE

Brand GenericIndicationPharmacologic CategoryKSEOther NotesUS Boxed warnings
Apresoline hydralazine HTN Direct arterial vasodilator hypotension, drug-induced lupus-like syndrome CI in CAD
Prozac fluoxetine MDD Selective serotonin reuptake inhibitor ssri drowsiness, insomnia, nausea, vomiting, xerostomia, sexual dysfunction, headache, diaphoresis CL within 14 days of MAOI; do not discontinue abruptly (all except fluoxetine)
Focalin XR methylphenidate ADHD, narcolepsy CNS stimulant insomnia, headache, anxiety, weight loss, decreased appetite, hypertension CI within 14 days of MAOI high potential for abuse
lopressor metoprolol tartrate AF (rate control), CAD, HTN Beta1-selective beta-blocker bradycardia, hypotension masks symptoms of hypoglycemia avoid abrupt discontinuation
Toprol-xl metoprolol succinate HF, AF (rate control), CAD, HTN Beta1-selective beta-blocker bradycardia, hypotension masks symptoms of hypoglycemia
Bactrim sulfamethoxazole/trimethoprim SSTI, cyctitis, pyelonephritis, opportunistic infection prophylaxis AA: MRSA, Enterobacteriaceae sulfonamide antibiotic nausea, vomiting diarrhea, skin rashes (rarely SJS or TEN), photosensitivity, crystalluria, hyperkalemia, increased serum creatinine, hypersensitivity reactions
Neurontin Gabapentin seizure disorders, neuropathic pain anticonvulsant somnolence, dizziness, ataxia, fatigue, diplopia, xerostomia, blurry vision, peripheral edema, weight gain
Klonophin Clonazepam Anxiety, seizure disorders benzodiazepine daytime sedation, performance impairment, tolerance, dependence, anterograde amnesia, withdrawal, dizziness, ataxia parenteral formulation contains propylene glycol and may be associated with toxicity if used >= 48 hours risk of profound sedation, respiratory depression, coma and death with opioids; risk of abuse, misuse, and addictions; risk of dependence and withdrawal reactions
Motrin, Advil Ibuprofen OA, RA, acute pain NSAID diarrhea, dyspepsia, abdominal pain, flatulence, nausea may reduce renal blood flow and compromise existing renal function (avoid in patients with renal disease, heart failure, and cirrhosis) may increase the risk of serious (and potentially fatal) cardiovascular thrombotic events, MI, and stroke; may increase the risk for serious (and potentially fatal) gastrointestinal adverse event including ulceration, bleeding, and perforation
Synthroid, Levoxyl, Unithroid levothyroxine Hypothyroidism Thyroid product weight loss, palpitations, diarrhea, insomnia, heat intolerance narrow therapeutic index drug (therapeutic monitoring is recommended); not all generic products are therapeutically equivalent not intended for use for weight loss
Omnicef cefdinir otitis media, bacterial sinusitis AA: streptococcus pneumoniae, haemophilus influenzae beta-lactam antibiotic ( third generation cephalosporin) diarrhea, hypersensitivity reactions
Tegretol carbamazepine seizure disorders, bipolar disorder anticonvulsant dizziness, drowsiness, headache, ataxia, nausea, vomiting, hyponatremia risk of serious dermatologic reactions (including SJS and TEN) in patients with certain genetic predisposition; may cause aplastic anemia and agranulocytosis
Xarelto rivaroxaban AF (stroke prevention), VTE, PAD anticoagulant, factor Xa inhibitor bleeding premature discontinuation increases risk of thrombotic events; increased risk of epidural or spinal hematoma in patient undergoing spinal puncture
tylenol acetaminophen pain, fever analgesic (non-opioid), antipyretic nausea, vomiting, increased hepatic transaminases total daily dose from all sources should not exceed maximum daily limit; hepatotoxicity
Lexapro escitalopram
Lipitor atorvastatin
lisinopril
acetaminophen/codeine
metformin
Norvasc amlodipine
Created by: user-1965903
 

 



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