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Bone tissues 3
| Question | Answer |
|---|---|
| What are the six major functions of bones | sturcture, protection, movement, mineral storage, blood, energy storage |
| Where does blood cell formation occur | in red bone marrow |
| Where is fat stored in the bone | yellow bone marrow |
| what mineral is especially stored in the bones | calcium |
| What percentage of bone matrix is mineral salts | 55% |
| What are the two lesser components of bone matrix | 15% water, 30% fibers and gels |
| which bone cell builds bone | osteoblasts |
| which bone cell breaks down bone | osteoclasts |
| Which mature bone cell maintains bone metabolism | osteocyte |
| Which bone cell develops into osteoblasts, and is the starter cell | osteoprogenitor cell |
| Which bone cell type is identified a as guide for undergoing cell division | osetoprogentior cell |
| What do osteoclasts use to digest bone matrix | acid and enzymes |
| what is diaphysis | the long body of shaft of the long bone |
| what is epiphysis | the proximal and distal end of the long bone |
| What is metaphysis | the region where the diaphysis and epiphysis meet, the growth plate is indeed here in the growing bone |
| What is articulated cartilage | hyaline cartliage covering the joint surfaces |
| What is periosteum | the dense outer membrane covering bone except at the joint surfaces |
| What is the medullary cavity | The cavity inside the diaphysis that contains tulle blood marrow and blood vessels in adults |
| What is endosteum | The thin membrane that lines the medulla are cavity, it contains bone forming cells |
| What is the difference between compact and spongy bone | compact is dense and contains osteons, spongy is bone marrow filled and contains no osteons |
| where is compact bone primarily located | on the outside of the bone |
| Where is spongy bone typically found | on the interior of the bone |
| What is trabeculae | Lattice like structure of spongy bone along stress lines |
| What is a osteon | A repeating structural unit of compact bone |
| What is concentic lamellae | Communion layers of mineralized matrix surrounding the central canal |
| What are lacunae | Small spaces that contain osteocytes |
| What are canaliculi | Tiny fluid filled channels that connect lucnae and the central canal |
| what is found in the central canal | blood vessels and lymphatic vessels |
| What do perforating canals do | Connect periosteum and endosteum and provide passageway for nerves and blood vessels |
| What us the difference between central and prefoating canals | Central canals run within osteons, perfoating canals connect the bones outer and inner regions |
| What are the main blood supplies to the bone | Periosteal, nutrient, metaphyseal, and epiphyseal arteries and veins. |
| What is the difference between intramembranous and endochondral ossification? | Intramembranous: bone forms directly within mesenchyme. Endochondral: bone forms within a hyaline cartilage model. |
| What are examples of intramembranous ossification? | Flat bones of the skull, facial bones, mandible, and parts of the clavicles. |
| What is an example of endochondral ossification? | Long-bone development. |
| What is the sequence of endochondral ossification? | Cartilage model → primary ossification center → medullary cavity develops in diaphysis → secondary ossification centers in epiphyses → articular cartilage and epiphyseal plate remain. |
| How does a bone grow in length? | Cartilage grows at the epiphyseal plate on the epiphyseal side and is replaced by bone on the diaphyseal side. |
| What is appositional growth? | Growth in thickness as osteoblasts add bone to the outer surface while osteoclasts enlarge the medullary cavity. |
| What happens in the resting zone of the epiphyseal plate? | Small, scattered chondrocytes anchor the plate to the epiphysis. |
| What happens in the proliferation zone? | Chondrocytes divide rapidly, stack like coins, and secrete extracellular matrix. |
| What happens in the hypertrophy zone? | Chondrocytes enlarge and mature in columns. |
| What happens in the calcification zone? | The cartilage matrix hardens and chondrocytes die. |
| What happens in the ossification zone? | Osteoblasts replace cartilage with bone. |
| What is the correct order of the five growth-plate zones? | Resting → Proliferation → Hypertrophy → Calcification → Ossification. |
| When does the epiphyseal plate typically close according to the lecture? | Around ages 18–21; the remnant is the epiphyseal line. The facts I would m |
| What is bone remodeling? | The ongoing replacement of old bone tissue with new bone tissue. |
| How does bone remodeling change with age in the lecture? | During growth, formation exceeds resorption; in young adulthood they are more balanced; in later adulthood, increased endosteal resorption relative to periosteal formation contributes to net bone loss. |
| What does parathyroid hormone (PTH) do to bone? | Increases the rate and number of osteoclasts. |
| What does calcitonin do? | Inhibits osteoclasts. |
| How much of the body's calcium is stored in bone according to the lecture? | 99% |
| What are the three main stages of fracture repair? | Reactive → Reparative → Remodeling. |
| What happens in the reactive phase of fracture repair? | A fracture hematoma forms; nearby bone cells die; swelling and inflammation occur; phagocytes and osteoclasts remove damaged tissue. |
| What happens in the reparative phase? | A fibrocartilaginous callus forms, followed by a bony callus; capillaries grow in and osteoblasts produce spongy bone trabeculae. |
| What happens in the remodeling phase? | The callus is remodeled, dead bone is resorbed, and compact bone replaces spongy bone. |
| What is the difference between open and closed reduction? | Closed reduction sets a fracture without surgery; open reduction sets it with surgery. |