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BDK Quiz 6
| Pharmacologic Category | Generic Name | Brand Name | Classification | Common Indications | Essential Knowledge |
|---|---|---|---|---|---|
| Alpha2 agonist | brimonidine (ophthalmic) | Alphagan P, Lumify | Lumify: OTC | Elevated IOP Ocular redness | Key Side Effects: ocular hypersensitivity, drowsiness, allergic conjunctivitis, conjunctival hyperemia, ocular pruritus Other Notes: CI with MAOI therapy |
| Non-selective beta-blocker | timolol (ophthalmic) | Timoptic, Timoptic XE, Istalol | Elevated IOP | Key Side Effects: blurred vision, ocular stinging and burning | |
| Prostaglandin analog | bimatoprost (ophthalmic) | Lumigan, Latisse | Elevated IOP, eyelash hypotrichosis | Key Side Effects: eyelash growth, conjunctival hyperemia, ocular pruritus, iris color change, periocular hyperpigmentation, blurred vision | |
| Prostaglandin analog | latanoprost (ophthalmic) | Xalatan, Xelpros, Iyuzeh | Elevated IOP | Key Side Effects: eyelash growth, conjunctival hyperemia, ocular pruritus, iris color change, periocular hyperpigmentation, blurred vision | |
| Calcineurin inhibitor | cyclosporin (ophthalmic) | Restasis | Keratoconjunctivitis sicca | Key Side Effects: ocular burning, stinging, pruritus, foreign body sensation, hypersensitivity reaction | |
| Pediculocide | permethrin (topical) | Nix, Elimite | Nix: OTC | Lice, scabies | Key Side Effects: itching, burning, redness, swelling of scalp |
| Retinoic acid derivative | adapalene (topical) | Differin | Acne | Key Side Effects: xeroderma, skin exfoliation, erythema, stinging, burning, pruritus | |
| Antiseptic | chlorhexidine (topical, PO) | Hibiclens, Peridex | Skin cleanser, periodontitis, gingivitis | Key Side Effects: dysgeusia, increased tartar formation, mouth discoloration, mouth irritation | |
| Corticosteroid | clobetasol (topical) | Temovate, Clobex | Psoriasis, atopic dermatitis | Key Side Effects: burning of skin, dryness of skin, hypopigmentation, secondary infection Other Notes: do not use for > 2 weeks because it may cause adrenal suppression | |
| Expectorant | guaifenesin (PO) | Mucinex, Robitussin, Robafen | OTC | Cough | Key Side Effects: nausea, vomiting, dizziness, headache, diarrhea, stomach pain |
| Antitussive | dextromethorphan (PO) | Delsym | OTC | Cough | Key Side Effects: nausea, drowsiness, dizziness, constipation Other Notes: CI within 14 days of MAOI |
| Antitussive | benzonatate (PO) | Tessalon Perles | Cough | Key Side Effects: sedation, nasal congestion, chills, chest numbness, bronchospasm Other Notes: do not break capsule because it may cause choking | |
| Alpha (α1) agonist | pseudoephedrine (PO) | Sudafed | OTC | Nasal congestion | Key Side Effects: Increased blood pressure, tachycardia, palpitations, insomnia, restlessness Other notes: sold behind the counter, avoid during first trimester of pregnancy |
| Corticosteroid | fluticasone (intranasal) | Flonase | OTC | Allergic rhinitis | Key Side Effects: nasal dryness, epistaxis, nasal burning, headache |
| Corticosteroid | triamcinolone (intranasal) | Nasacort | OTC | Allergic rhinitis | Key Side Effects: nasal dryness, epistaxis, nasal burning, headache |
| Histamine (H1) blocker | azelastine (intranasal) | Astepro | OTC | Allergic rhinitis | Key Side Effects: headache, nasal dryness, epistaxis, bitter taste, drowsiness |
| Histamine (H1) blocker | diphenhydramine (PO, IV) | Benadryl | OTC | Allergic rhinitis, allergic reaction, insomnia | Key Side Effects: drowsiness, constipation, xerostomia, urinary retention, cognitive impairment Other Notes: for OTC use, do NOT use in children < 6 years of age |
| Histamine (H1) blocker | hydroxyzine (PO, IV) | Atarax, Vistaril | Pruritus, nausea, anxiety | Key Side Effects: dizziness, somnolence, xerostomia, blurred vision, QTc prolongation | |
| Histamine (H1) blocker | cetirizine (PO) | Zyrtec | OTC | Allergic rhinitis | Key Side Effects: drowsiness, dizziness, headache |
| Histamine (H1) blocker | loratadine (PO) | Claritin | OTC | Allergic rhinitis | Key Side Effects: drowsiness, dizziness, headache |
| Histamine (H1) blocker | fexofenadine (PO) | Allegra | OTC | Allergic rhinitis | Key Side Effects: drowsiness, dizziness, headache |
| Histamine (H1) blocker | levocetirizine (PO) | Xyzal | OTC | Allergic rhinitis | Key Side Effects: diarrhea, drowsiness, headache |
| Histamine (H1) blocker | olopatadine (ophthalmic) | Pataday, Patanol | OTC | Allergic conjunctivitis | Key Side Effects: ocular burning, discomfort, dryness |
| Histamine (H1) blocker and opioid analgesic | promethazine and codeine (PO) | Phenergan with Codeine | CS-V | Cough | Key Side Effects: dizziness, somnolence, xerostomia, blurred vision, constipation, respiratory depression (dose-related) US Boxed Warning: concomitant use of opioids with benzodiazepines or other CNS depressants (including alcohol), may result in profound sedation, respiratory depression, coma, and death Other Notes: opioid-containing cough and cold products no longer indicated for use in patients <18 years of age |
| Opioid analgesic and expectorant | codeine and guaifenesin (PO) | Robitussin AC, Cheratussin AC | CS-V | Cough | Key Side Effects: dizziness, somnolence, constipation, respiratory depression (dose-related) Other Notes: opioid-containing cough and cold products no longer indicated for use in patients <18 years of age |
| 5 alpha-reductase inhibitor | finasteride (PO) | Proscar, Propecia | BPH, male pattern baldness | Key Side Effects: sexual dysfunction Other Notes: women who are of child-bearing age should not touch | |
| Alpha1 blocker | doxazosin (PO) | Cardura, Cardura XL | BPH, HTN | Key Side Effects: dizziness, orthostatic hypotension, intraoperative floppy iris syndrome (rare) | |
| Alpha1a blocker | tamsulosin (PO) | Flomax | BPH | Key Side Effects: dizziness, ejaculation failure, intraoperative floppy iris syndrome (rare) Other Notes: take 30 minutes after the same meal daily | |
| Anticholinergic | solifenacin (PO) | Vesicare | Overactive bladder | Key Side Effects: xerostomia, constipation Other Notes: CI in uncontrolled narrow-angle glaucoma | |
| Anticholinergic, urinary antispasmodic agent | oxybutynin (PO, patch) | PO: Ditropan XL, Patch: Oxytrol, Oxytrol for Women | OTC | Overactive bladder | Key Side Effects: xerostomia, constipation, dizziness, drowsiness Other Notes: CI in uncontrolled narrow-angle glaucoma |
| Beta3 agonist | mirabegron (PO) | Myrbetriq | Overactive bladder | Key Side Effects: hypertension | |
| Urinary analgesic | phenazopyridine (PO) | Pyridium, Azo Urinary Pain Relief | OTC | Symptomatic relief of dysuria | Key Side Effects: stomach cramps, headache, dizziness Other Notes: may change bodily fluids red/orange |
| Electrolyte supplement | magnesium sulfate (IV, IM) | --- | Hypomagnesemia, pre-eclampsia | Key Side Effects: flushing, hypotension, cardiac arrest with rapid undiluted IV infusion Other Notes: dilute before infusion | |
| Electrolyte supplement | potassium chloride (PO, IV) | PO: K-Tab, Klor-Con, Micro-K | Hypokalemia | Key Side Effects (IV): hyperkalemia, cardiac arrest with rapid undiluted infusion Key Side Effects (PO): hyperkalemia, abdominal discomfort/pain, diarrhea, flatulence, nausea, vomiting Other Notes: dilute before infusion; do not administer IV push; vesicant; tablets with wax coating may appear in stool; take oral forms with meals and a full glass of water | |
| Colloid | albumin, 5% or 25% (IV) | Albutein, AlbuRx | Hypovolemia, SBP, paracentesis | Key Side Effects: edema | |
| Crystalloid | 0.9% sodium chloride (IV) | Normal saline | Hypovolemia | Key Side Effects: hypervolemia, non-anion gap metabolic acidosis | |
| Crystalloid | lactated ringers (IV) | LR | Hypovolemia | Key Side Effects: hypervolemia | |
| Crystalloid | 5% dextrose in water (IV) | D5W | Carrier fluid, hypoglycemia, hypernatremia | Key Side Effects: hyperglycemia, hyponatremia, hypervolemia | |
| Phosphate binder | Calcium acetate (PO) | Calphron, Phoslo | OTC | Hyperphosphatemia | Key Side Effects: hypercalcemia, nausea, vomiting, constipation Other notes: Each dose of 667mg contains 169mg of elemental calcium |