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Chapter 16

Blood-Modifying, Antineoplastic, and Immunosuppressant Drugs

QuestionAnswer
Cell cycle–nonspecific Capable of acting in several or all cell cycle phases.
Cell cycle–specific Capable of acting during a particular cell cycle phase only.
Cytotoxic Capable of destroying cells.
Disseminated intravascular coagulation (DIC) Widespread formation of clots (thrombi) in the microscopic blood vessels of the circulatory system. DIC occurs as a complication of a wide variety of disorders and consumes clotting factors, with resultant bleeding.
Endothelial layer The smooth layer of epithelial cells that line blood vessels.
Erythropoietin A glycoprotein hormone secreted mainly by the kidney; it acts on stem cells of the bone marrow to stimulate red blood cell production.
Fibrinolysis Fibrin (clot) breakdown through the action of the enzyme plasmin.
Hybridoma A cell culture that consists of a clone of a hybrid cell formed by fusing cells of different types, such as stimulated mouse plasma cells and myeloma cells
Metastasis Generally, refers to the transfer of cancer cells from one site to another.
Myeloma A malignant neoplasm of plasma cells (B lymphocytes).
Myelosuppression Inhibition of bone marrow activity that results in decreased production of blood cells and platelets.
Thrombocytopenia A decreased number of platelets.
Thromboembolism The condition that occurs when thrombus material becomes dislodged and is transported by the bloodstream to another site.
Thrombus A clot in the circulatory system.
Vesicant A substance that causes blister formation.
Created by: Radicalentity888
 

 



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