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Hydro/Fludrocortison
| Question | Answer |
|---|---|
| What drug is used for decreased cortisol? | Hydrocortisone |
| What drug is used for decreased aldosterone? | Fludrocortisone |
| When does hydrocortisone replace cortisol? What does it support? | Hydrocortisone replaces cortisol when the body cannot produce enough. Supports stress response, helps maintain BP, glucose metabolism, and influences immune responses |
| What should you monitor for patients on hydrocortisone | Monitor weight, fluid status, glucose, infection, can lead to HTN/fluid retention, and GI effects. |
| What time of day is a larger dose of hydrocortisone given | Larger dose earlier in the day to better approximate normal cortisol physiology. |
| Adrenal under replacement | Fatigue/weakness. hypotension, hypoglycemia, worsening illness |
| Adrenal over replacement | hyperglycemia, hypertension, fluid/weight gain, infection risk |
| FLudrocortisone replaces _____ in ______ | Fludrocortisone replaces aldosterone in primary adrenal inssuficiency |
| What does aldosterone do? | Hold sodium and water, excretes potassium |
| Too little aldosterone leads to | Hypotension, orthrostasis, salt craving, hyperkalemia |
| TOo much aldosterone leads too | Hypertension, edema/fluid retention, hypokalemia |
| Primary adrenal insufficiency can require both hydrocortisone and fludrocortisone; true or false | True. |