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Deferoxamine

QuestionAnswer
Deferoxamine T, P T: Removes excess iron P: Antidote/ heavy metal antagonist
MOA Deferoxamine Binds to unbound iron and removes it from the bloodstream, it is then excreted by the kidneys
uses for Deferoxamine acute iron toxicity ingestion, or repeated blood transfusions
Side/adverse effects to Deferoxamine Vision changes, hearing loss, tinnitus, hypertension, tachycardia, abdominal pain, N/V/D, red urine, leg cramps, nephrotoxic, tachycardia, myalgia
Interactions with Deferoxamine Ascorbic acid increases efficacy of the drug, increasing cardiac toxicity.
Contraindications to Deferoxamine Patients with severe renal disease, pregnancy
Deferoxamine labs LFTs, renal panel, ferritin, level
Nursing considerations Assess hearing/vision every 3 months, renal, lfts, ferritin levels, monitor vital signs
Education Deferoxamine Contraception to avoid pregnancy. Maybe on vit c, caution not to take too much due to risk of cardiac toxicity.
Created by: pharm3studysets
 

 



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