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Deferasirox

QuestionAnswer
Deferasirox T, P Removes excess iron, Antidote chelating agent
MOA Deferasirox Binds with iron and excretes it in stool
Uses for Deferasirox Iron toxicity from multiple transfusions or thalassemia
Side/adverse effects of Deferasirox N/V/D, headache, dizziness, ototoxicity, visual disturbance, cough, GI bleed, abd pain, cephroexic, hepatotoxic, SJS, bm suppression, fever
Contraindications Deferasirox With theophylline, pts with myelodysplastic syndrom eor advanced malignancies, hepatic impairment
Deferasirox interactions CYP drug; can increase/decrease effectiveness, aluminum antacids, nsaids, corticosteroids, biphosphates, anticoagulants
LABs for Deferasirox ALT, AST, Renal, CBC, ferritin
Nursing considerations for Deferasirox Assess hearing and vision, CBC renal panel, ferritin, LFTs every 2 weeks
When to take Deferasirox Take on empty stomach or 30 minutes before meal
What should the pills be dissolved in? OJ, H2O, apple juice, and drink immediately
When is the med held? If platelets less than 50 the med must be held.
Created by: pharm3studysets
 

 



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